Drug design for neglected disease in Brazil

J Giarolla, E Igne Ferreira - Mini Reviews in Medicinal …, 2015 - ingentaconnect.com
Neglected tropical diseases (NTD) are a group of 17 diseases transmitted by virus, protozoa,
helminthes and bacteria. These illnesses are responsible for millions of deaths per year …

Dipole moment in medicinal research: green and sustainable approach

A Das, BK Banik - Green Approaches in Medicinal Chemistry for …, 2024 - Elsevier
In this study, the synthesis, biological activity, and structure-activity relationships of diverse
compounds are described. In general, the relationships between dipole moments and …

[PDF][PDF] Studies on dipole moment of penicillin isomers and related antibiotics

A Das, BK Banik - J Indian Chem Soc, 2020 - indianchemicalsociety.com
In this study, the relationships between dipole moment and medicinal activity of penicillin
derivatives are discussed. Four derivatives of penicillin and the stereoisomers of penicillin G …

Anti‐Malarial and Multi‐Bioactive Co (II), Cu (II) and Ni (II) Salen Complexes: Synthesis, Characterization and Computational Studies

MA Todarwal, RS Sancheti, SR Nikume… - Chemistry & …, 2024 - Wiley Online Library
Herein, we report the anti‐malarial, anti‐bacterial and anti‐inflammatory activities of the
N2O2 donor tetradentate salen type ligand and its CoL, NiL, and CuL metal complexes. The …

Dipole moment studies on beta lactams

A Das, BK Banik - Green Approaches in Medicinal Chemistry for …, 2024 - Elsevier
Abstract β-Lactams are extremely important molecules in the field of medicine. Penicillins,
cephalosporins, carbapenems, thienamycins, cephalosporins, monobactams, and …

Ester of Quinoxaline-7-carboxylate 1, 4-di-N-oxide as Apoptosis Inductors in K-562 Cell Line: An in vitro, QSAR and DFT Study

G Rivera, S Andrade-Ochoa… - Anti-Cancer Agents …, 2017 - ingentaconnect.com
Background: Quinoxalines have shown a wide variety of biological activities including as
antitumor agents. The aims of this study were to evaluate the activity of quinoxaline 1, 4-di-N …

The Effects of Dipole Moments on the Biological Activities of Diverse Beta-Lactams

A Das, BK Banik - Chemistry and Biology of Beta-Lactams, 2024 - books.google.com
A dipole is basically a system containing two poles, which happen to be opposite to each
other in nature. A dipole is characterized by its dipole moment (µ), a measurement of the …

Inherent Flexibility vis‐à‐vis Structural Rigidity in Chemically Stable Antimalarial Dispiro N‐Sulfonylpiperidine Tetraoxanes

C Sharma, K Sharma, J Kumar Yadav… - …, 2018 - Wiley Online Library
Structurally diverse and chemically stable tetraoxanes were formed by peroxidation of N‐
sulfonylpiperidones. X‐ray analysis revealed that the crystal structures possess central spiro …

Otimização de compostos de quinolina para Doenças Negligenciadas. Bloqueio de vias de metabolização

CN Carrilho - 2016 - repositorio.ul.pt
Segundo a organização mundial de saúde (OMS) estima-se que tenham ocorrido
globalmente cerca de 200 milhões de casos de malária em 2013 e 1, 6 milhões de novos …