Mitochondria play a key role in iron metabolism in that they synthesize heme, assemble iron–
sulfur (Fe/S) proteins, and participate in cellular iron regulation. Here, we review the latter …

Covering: up to 2014 Siderophores are chelators synthesized by microbes to sequester iron.
This article summarizes the knowledge on the fungal siderophore metabolism with a focus …

Trichoderma spp. are a rich source of secondary metabolites (SMs). The recent publication
of the genome sequences of three Trichoderma spp. has revealed a vast repertoire of genes …

Iron is the most abundant transition metal in the human body and its bioavailability is
stringently controlled. In particular, iron is tightly bound to host proteins such as transferrin to …

To maintain iron homeostasis, fungi have to balance iron acquisition, storage, and utilization
to ensure sufficient supply and to avoid toxic excess of this essential trace element. As …

Iron is essential for a wide range of cellular processes. Here we show that the bZIP-type
regulator HapX is indispensable for the transcriptional remodeling required for adaption to …

Aspergillus flavus is a diverse assemblage of strains that include aflatoxin-producing and
non-toxigenic strains with cosmopolitan distribution. The most promising strategy currently …

Iron is an essential but, in excess, toxic nutrient. Therefore, fungi evolved fine-tuned
mechanisms for uptake and storage of iron, such as the production of siderophores (low …

Sterol regulatory element binding proteins (SREBPs) are a class of basic helix-loop-helix
transcription factors that regulate diverse cellular responses in eukaryotes. Adding to the …

Fungal pathogens must assimilate local nutrients to establish an infection in their
mammalian host. We focus on carbon, nitrogen, and micronutrient assimilation mechanisms …