Zinc-finger proteins (ZNFs) are one of the most abundant groups of proteins and have a
wide range of molecular functions. Given the wide variety of zinc-finger domains, ZNFs are …

Notch signaling is an evolutionarily conserved pathway that regulates important biological
processes, such as cell proliferation, apoptosis, migration, self-renewal, and differentiation …

Cancer-secreted, extracellular vesicle (EV)–encapsulated miRNAs enable cancer cells to
communicate with each other and with noncancerous cells in tumor pathogenesis and …

Identifying gene expression differences in heterogeneous tissues across conditions is a
fundamental biological task, enabled by multi-condition single-cell RNA sequencing (RNA …

LMO2 was first discovered through proximity to frequently occurring chromosomal
translocations in T cell acute lymphoblastic leukaemia (T-ALL). Subsequent studies on its …

Background. The critical role of vascular health on brain function has received much
attention in recent years. At the single‐cell level, studies on the developmental processes of …

As a key hub of malignant properties, the cancer microenvironment plays a crucial role
intimately connected to tumor properties. Accumulating evidence supports that the …

Alterations of histone methylation dynamically regulated by methyltransferases and
demethylases are frequently found in human cancers. Here, we showed that expression of …

Summary Inhibitor of differentiation 1 (ID1) is highly expressed in glioblastoma stem cells
(GSCs). However, the regulatory mechanism responsible for its role in GSCs is poorly …

P14ARF (ARF; Alternative Reading Frame) is an extensively characterized tumor
suppressor which, in response to oncogenic stimuli, mediates cell cycle arrest and apoptosis …