Intracellular galectins are carbohydrate-binding proteins capable of sensing and repairing
damaged lysosomes. As in the physiological conditions glycosylated moieties are mostly in …

Crohn′ s disease (CD) is an inflammatory bowel disease (IBD) that can affect the whole
gastrointestinal tract. The ileocolonic variant of CD, an inflammation of both the ileum and …

US10226238B2 - Non-invasive methods of detecting target molecules - Google Patents
US10226238B2 - Non-invasive methods of detecting target molecules - Google Patents Non-invasive …

Proteolysis is arguably the most important of all post-translational modifications in that it is
effectively irreversible, and leads to the partial or complete breakdown of proteins. Cells …

Zymogen granules (ZG) are specialized organelles in the exocrine pancreas which allow
digestive enzyme storage and regulated secretion. The molecular mechanisms of their …

Zymogen granule (ZG) constituents play important roles in pancreatic injury and disease. In
previous studies, proteomic analyses with rat zymogen granules were separated by two …

The exocrine pancreas produces and secretes multiple digestive enzymes and has been the
model in which the structure and functional organization of the mammalian secretory …

A molecular model of pancreatic zymogen granule (ZG) is critical for understanding its
functions. We have extensively characterized the composition and membrane topology of rat …

ObjectiveObesity is a risk factor for psychiatric diseases. Recently, a number of single
nucleotide polymorphisms (SNPs) have been shown to be related to body mass index (BMI) …

Zymogen granules (ZG) are specialized organelles in the exocrine pancreas which allow
digestive enzyme storage and regulated secretion. To investigate ZG biogenesis, cargo …