Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic

KKW To, S Sridhar, KHY Chiu, DLL Hung… - Emerging microbes & …, 2021 - Taylor & Francis
Without modern medical management and vaccines, the severity of the Coronavirus
Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) …

Consistent detection of 2019 novel coronavirus in saliva

KKW To, OTY Tsang, CCY Yip, KH Chan… - Clinical Infectious …, 2020 - academic.oup.com
Abstract The 2019 novel coronavirus (2019-nCoV) was detected in the self-collected saliva
of 91.7%(11/12) of patients. Serial saliva viral load monitoring generally showed a declining …

Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-PCR assay validated in …

JFW Chan, CCY Yip, KKW To, THC Tang… - Journal of clinical …, 2020 - Am Soc Microbiol
ABSTRACT On 31 December 2019, the World Health Organization was informed of a cluster
of cases of pneumonia of unknown etiology in Wuhan, China. Subsequent investigations …

A familial cluster of infection associated with the 2019 novel coronavirus indicating possible person-to-person transmission during the incubation period

P Yu, J Zhu, Z Zhang, Y Han - The Journal of infectious diseases, 2020 - academic.oup.com
An ongoing outbreak of pneumonia associated with 2019 novel coronavirus was reported in
China. It is unclear whether the virus is infective exists during the incubation period …

Performance of saliva, oropharyngeal swabs, and nasal swabs for SARS-CoV-2 molecular detection: a systematic review and meta-analysis

RA Lee, JC Herigon, A Benedetti… - Journal of clinical …, 2021 - Am Soc Microbiol
Nasopharyngeal (NP) swabs are considered the highest-yield sample for diagnostic testing
for respiratory viruses, including SARS-CoV-2. The need to increase capacity for SARS-CoV …

Clinical evaluation of self-collected saliva by quantitative reverse transcription-PCR (RT-qPCR), direct RT-qPCR, reverse transcription–loop-mediated isothermal …

M Nagura-Ikeda, K Imai, S Tabata… - Journal of clinical …, 2020 - Am Soc Microbiol
The clinical performances of six molecular diagnostic tests and a rapid antigen test for
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were clinically evaluated …

Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort …

KKW To, OTY Tsang, WS Leung, AR Tam… - The Lancet infectious …, 2020 - thelancet.com
Summary Background Coronavirus disease 2019 (COVID-19) causes severe community
and nosocomial outbreaks. Comprehensive data for serial respiratory viral load and serum …

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

JFW Chan, S Yuan, KH Kok, KKW To, H Chu, J Yang… - The lancet, 2020 - thelancet.com
Background An ongoing outbreak of pneumonia associated with a novel coronavirus was
reported in Wuhan city, Hubei province, China. Affected patients were geographically linked …

Advanced point‐of‐care testing technologies for human acute respiratory virus detection

Z Zhang, P Ma, R Ahmed, J Wang, D Akin… - Advanced …, 2022 - Wiley Online Library
The ever‐growing global threats to human life caused by the human acute respiratory virus
(RV) infections have cost billions of lives, created a significant economic burden, and …