Due to the potential use as transfecting agents of nucleic acids (DNA or RNA), multivalent
cationic non-viral vectors have received special attention in the last decade. Much effort has …

The use of cationic lipids (CLs) as transfecting agents of DNA has received an increasing
attention in the last two decades. In order to improve the transfection efficiency with lower …

This feature article describes the recent developments in the design of cationic lipids and
their applications in gene delivery. Various structure–activity investigations explaining the …

Cationic liposomes (CLs) composed of 3β-[N-(N′, N′-dimethylaminoethane) carbamoyl]
cholesterol (DC-Chol) and dioleoylphosphatidylethanolamine (DOPE)(DC-Chol/DOPE …

The aim of this work was to improve the transfection efficacy of solid lipid nanoparticle (SLN)-
based non-viral vectors into ARPE-19 cells through the addition of Sweet Arrow Peptide …

New polycationic lipids corresponding to the two different classes of amphiphiles (“head-tail”
and “gemini”) were designed and used as components of non-viral gene delivery systems …

Polyhexamethylene biguanide (PHMB) has been used increasingly in various applications
because of antibacterial properties; however, its cytotoxicity hampers application. On the …

The therapeutic potential of antisense oligonucleotides (ASODN) is primarily dependent
upon its safe and efficient delivery to specific cells overcoming degradation and maximizing …

Retinal pigment epithelial (RPE) cells are usually employed to study DNA systems for
diseases related to problems in the retina. Solid lipid nanoparticles (SLNs) have been …

The development of a tumor-specific immunoliposome delivering small interfering RNA
(siRNA) represents a practical way in cancer gene therapy. In this study, we developed …