Cancer cells characterized by uncontrolled growth and proliferation require altered
metabolic processes to maintain this characteristic. Metabolic reprogramming is a process …

Skeletal muscle atrophy is a well-known consequence of spaceflight. Because of the
potential significant impact of muscle atrophy and muscle dysfunction on astronauts and …

Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Skeletal muscle development and regeneration is governed by the combined action of Myf5,
MyoD, Mrf4 and MyoG, also known as the myogenic regulatory factors (MRFs). These …

Myogenesis is a complex biological process, and understanding the regulatory network of
skeletal myogenesis will contribute to the treatment of human muscle related diseases and …

Skeletal muscle myogenesis and injury-induced muscle regeneration contribute to muscle
formation and maintenance. As myogenic stem cells, skeletal muscle satellite cells have the …

Sarcopenia is a serious public health problem associated with the loss of muscle mass and
function. The purpose of this study was to identify molecular markers and construct a ceRNA …

Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis.
Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass …

Prolonged unloading of skeletal muscle, a common outcome of events such as spaceflight,
bed rest and hindlimb unloading, can result in extensive metabolic, structural and functional …

Muscle atrophy is associated with negative outcomes in a variety of diseases. Identification
of a common therapeutic target would address a significant unmet clinical need. Here, we …