[HTML][HTML] The magnitude and predictors of abandonment of therapy in paediatric acute leukaemia in middle-income countries: a systematic review and meta-analysis

S Gupta, S Yeh, A Martiniuk, CG Lam, HY Chen… - European Journal of …, 2013 - Elsevier
BACKGROUND: Abandonment of therapy is a significant cause of paediatric cancer
treatment failure in low-to middle-income countries (LMIC), but its impact has been …

Mitochondrial remodeling in cancer metabolism and survival: potential for new therapies

IA Barbosa, NG Machado, AJ Skildum, PM Scott… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Mitochondria are semi-autonomous organelles that play essential roles in cellular
metabolism and programmed cell death pathways. Genomic, functional and structural …

Mitochondrial dependency in progression of acute myeloid leukemia

NP Basak, S Banerjee - Mitochondrion, 2015 - Elsevier
Acute myeloid leukemia (AML) is a clonal hematopoietic malignant disorder which arises
due to dysregulated differentiation, uncontrolled growth and inhibition of apoptosis leading …

Ancient mitochondrial and modern whole genomes unravel massive genetic diversity loss during near extinction of Alpine ibex

M Robin, G Ferrari, G Akgül, X Münger… - Molecular …, 2022 - Wiley Online Library
Population bottlenecks can have dramatic consequences for the health and long‐term
survival of a species. Understanding of historic population size and standing genetic …

Outcome of pediatric acute myeloid leukemia (AML) in low-and middle-income countries: a systematic review of the literature

RE Van Weelderen, K Klein… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Survival rates of pediatric acute myeloid leukemia (AML) in low-and middle-
income countries (LMICs) seem extremely poor, and the available literature on the matter is …

Somatic mitochondrial DNA mutations in human cancers

M Yu - Advances in clinical chemistry, 2012 - books.google.com
Mitochondria are ubiquitous organelles in eukaryotic cells principally responsible for
regulating cellular energy metabolism, free radical production, and the execution of …

Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer

Y Li, K Sundquist, S Vats, MG Hong, X Wang… - Journal of Translational …, 2023 - Springer
Background Breast cancer is, despite screening, not always detected early enough and is
together with other tumor types known to shed genetic information in circulation. Unlike …

Physiology and pathophysiology of mitochondrial DNA

H Li, D Liu, J Lu, Y Bai - Advances in Mitochondrial Medicine, 2012 - Springer
Mitochondria are the only organelles in animal cells which possess their own genomes.
Mitochondrial DNA (mtDNA) alterations have been associated with various human …

Mitochondrial DNA variation analysis in cervical cancer

SP Kabekkodu, S Bhat, R Mascarenhas, S Mallya… - Mitochondrion, 2014 - Elsevier
This study was undertaken to investigate the mitochondrial DNA (mtDNA) variation in non-
malignant and malignant cervical tissue samples. We have identified 229 and 739 variations …

Mitochondrial gene expression signature predicts prognosis of pediatric acute myeloid leukemia patients

S Chaudhary, S Ganguly, JK Palanichamy… - Frontiers in …, 2023 - frontiersin.org
Introduction Gene expression profile of mitochondrial-related genes is not well deciphered
in pediatric acute myeloid leukaemia (AML). We aimed to identify mitochondria-related …