▪ Abstract Protein S-palmitoylation is the thioester linkage of long-chain fatty acids to
cysteine residues in proteins. Addition of palmitate to proteins facilitates their membrane …

▪ Abstract The sequestration and delivery of cytoplasmic material to the yeast vacuole and
mammalian lysosome require the dynamic mobilization of cellular membranes and …

Compatibility between host cells and heterologous pathways is a challenge for constructing
organisms with high productivity or gain of function. Designer yeast cells incorporating the …

Nucleus-vacuole (NV) junctions in Saccharomyces cerevisiae are formed through specific
interactions between Vac8p on the vacuole membrane and Nvj1p in the nuclear envelope …

Vac8p is a vacuolar membrane protein that is required for efficient vacuole inheritance and
fusion, cytosol-to-vacuole targeting, and sporulation. By analogy to other armadillo domain …

Armadillo (Arm) repeat proteins contain tandem copies of a degenerate protein sequence
motif that forms a conserved three-dimensional structure. Animal Arm repeat proteins …

We have been studying protein components that function in the cytoplasm to vacuole
targeting (Cvt) pathway and the overlapping process of macroautophagy. The Vac8 and …

Oxysterol binding protein (OSBP) is the only protein known to bind specifically to the group
of oxysterols with potent effects on cholesterol homeostasis. Although the function of OSBP …

▪ Abstract The vacuole/lysosome of the budding yeast Saccharomyces cerevisiae is actively
divided between mother and daughter cells. Vacuole inheritance initiates early in the cell …

Protein palmitoylation or, more specifically, S‐acylation is a reversible post‐translational
lipid modification. Despite the identification of several proteins that are altered in this way …