Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
Exosome: a review of its classification, isolation techniques, storage, diagnostic and targeted therapy applications
Y Zhang, J Bi, J Huang, Y Tang, S Du… - International journal of …, 2020 - Taylor & Francis
Exosomes are nano-sized small extracellular vesicles secreted by cells, carrying nucleic
acids, proteins, lipids and other bioactive substances to play a role in the body's …
acids, proteins, lipids and other bioactive substances to play a role in the body's …
[HTML][HTML] Advances in oligonucleotide drug delivery
TC Roberts, R Langer, MJA Wood - Nature reviews Drug discovery, 2020 - nature.com
Oligonucleotides can be used to modulate gene expression via a range of processes
including RNAi, target degradation by RNase H-mediated cleavage, splicing modulation …
including RNAi, target degradation by RNase H-mediated cleavage, splicing modulation …
[HTML][HTML] RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
[HTML][HTML] Exosomes, a new star for targeted delivery
H Chen, L Wang, X Zeng, H Schwarz… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing
numerous biological molecules including nucleic acids, proteins and lipids, which are …
numerous biological molecules including nucleic acids, proteins and lipids, which are …
[HTML][HTML] Dosing extracellular vesicles
D Gupta, AM Zickler, S El Andaloussi - Advanced drug delivery reviews, 2021 - Elsevier
Extracellular vesicles (EVs) are natural nanoparticles containing biologically active
molecules. They are important mediators of intercellular communication and can be …
molecules. They are important mediators of intercellular communication and can be …
Engineered extracellular vesicles and their mimetics for cancer immunotherapy
C Liu, Y Wang, L Li, D He, J Chi, Q Li, Y Wu… - Journal of Controlled …, 2022 - Elsevier
Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by living
cells that are involved in many physiological and pathological processes as intermediaries …
cells that are involved in many physiological and pathological processes as intermediaries …
Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source
W Meng, C He, Y Hao, L Wang, L Li, G Zhu - Drug delivery, 2020 - Taylor & Francis
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …
Advances in therapeutic applications of extracellular vesicles
Extracellular vesicles (EVs) are nanometer-sized, lipid membrane–enclosed vesicles
secreted by most, if not all, cells and contain lipids, proteins, and various nucleic acid …
secreted by most, if not all, cells and contain lipids, proteins, and various nucleic acid …
Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …