Liquid Biopsy Based on Cell-Free DNA and RNA

C Loy, L Ahmann, I De Vlaminck… - Annual Review of …, 2024 - annualreviews.org
This review delves into the rapidly evolving landscape of liquid biopsy technologies based
on cell-free DNA (cfDNA) and cell-free RNA (cfRNA) and their increasingly prominent role in …

Non-invasive prenatal diagnosis (NIPD): how analysis of cell-free DNA in maternal plasma has changed prenatal diagnosis for monogenic disorders

B Hanson, E Scotchman, LS Chitty… - Clinical …, 2022 - portlandpress.com
Cell-free fetal DNA (cffDNA) is released into the maternal circulation from trophoblastic cells
during pregnancy, is detectable from 4 weeks and is representative of the entire fetal …

Position statement from the International Society for Prenatal Diagnosis on the use of non‐invasive prenatal testing for the detection of fetal chromosomal conditions in …

L Hui, K Ellis, D Mayen, MD Pertile… - Prenatal …, 2023 - Wiley Online Library
Key points What is already known about this topic? In 2015, the International Society for
Prenatal Diagnosis (ISPD) published its first position statement on the use of non‐invasive …

Routinization of prenatal screening with the non-invasive prenatal test: pregnant women's perspectives

KRM van der Meij, A Njio, L Martin… - European Journal of …, 2022 - nature.com
Due to the favorable test characteristics of the non-invasive prenatal test (NIPT) in the
screening of fetal aneuploidy, there has been a strong and growing demand for …

Ethical issues associated with prenatal screening using non‐invasive prenatal testing for sex chromosome aneuploidy

M Johnston, C Warton, MD Pertile… - Prenatal …, 2023 - Wiley Online Library
Prenatal screening for sex chromosome aneuploidies (SCAs) is increasingly available
through expanded non‐invasive prenatal testing (NIPT). NIPT for SCAs raises complex …

Experiences of pregnant women with genome-wide non-invasive prenatal testing in a national screening program

KRM van der Meij, QYF van de Pol… - European Journal of …, 2023 - nature.com
Pregnant women's perspectives should be included in the dialogue surrounding the
expanding offers of non-invasive prenatal testing (NIPT), especially now that technological …

A cross‐country comparison of pregnant women's decision‐making and perspectives when opting for non‐invasive prenatal testing in the Netherlands and Belgium

L Lannoo, KRM van der Meij, MN Bekker… - Prenatal …, 2023 - Wiley Online Library
Abstract Background The Netherlands and Belgium have been among the first countries to
offer non‐invasive prenatal testing (NIPT) as a first‐tier screening test. Despite similarities …

Non-invasive prenatal testing in Germany: a unique ethical and policy landscape

H Bowman-Smart, C Wiesemann, R Horn - European Journal of Human …, 2023 - nature.com
Non-invasive prenatal testing (NIPT) has been available commercially in Europe since
approximately 2012. Currently, many countries are in the process of integrating NIPT into …

Issues associated with possible implementation of Non‐Invasive Prenatal Testing (NIPT) in first‐tier screening: A rapid scoping review

M Ghiasi, C Armour, M Walker, N Shaver… - Prenatal …, 2023 - Wiley Online Library
In recent years, as the implementation and use of Non‐Invasive Prenatal Testing (NIPT)
have increased, the cost of the test has been decreasing. The cost of NIPT is expected to fall …

Non-invasive prenatal testing (NIPT): is routinization problematic?

C Rehmann-Sutter, DRM Timmermans, A Raz - BMC medical ethics, 2023 - Springer
Background The introduction and wide application of non-invasive prenatal testing (NIPT)
has triggered further evolution of routines in the practice of prenatal diagnosis.'Routinization' …