Long-term clinical repair of articular cartilage remains elusive despite advances in cartilage
tissue engineering. Only one cartilage repair therapy classified as a “cellular and gene …

Efforts to develop effective disease-modifying drugs to treat osteoarthritis have so far proved
unsuccessful with a number of promising drug candidates from pre-clinical studies failing to …

OBJECTIVE: Radiographic interpretation suffers from an ever-increasing workload in
orthopedic and radiology departments. The present study applied and assessed the …

Knee Osteoarthritis (OA) is a destructive joint disease identified by joint stiffness, pain, and
functional disability concerning millions of lives across the globe. It is generally assessed by …

Subchondral bone cysts represent an early postoperative sign associated with many
articular cartilage repair procedures. They may be defined as an abnormal cavity within the …

Bone marrow lesions (BMLs), which are early signs of osteoarthritis (OA) that are associated
with the presence, onset and severity of pain, represent an emerging imaging biomarker and …

Subchondral lucency (SCL), also referred to as subchondral bone cysts, can cause clinical
problems in horses and humans. In humans, SCLs occur in youths and adolescents [1] due …

Introduction Age and gender have been reported to have a remarkable impact on bone
homeostasis. However, subchondral bone, which plays a pivotal role in the initiation and …

Osteoarthritis (OA) is a disease of human joints, especially the knee joint, due to significant
weight of the body. This disease leads to rupture and degeneration of parts of the cartilage …

Objective To evaluate change in bone mineral density (BMD) during development of knee
osteoarthritis (OA) in elderly Chinese community residents. Further, to monitor disease …