[图书][B] ROC analysis for classification and prediction in practice
This book presents a unified and up-to-date introduction to ROC methodologies, covering
both diagnosis (classification) and prediction. The emphasis is on the conceptual …
both diagnosis (classification) and prediction. The emphasis is on the conceptual …
Construction of confidence intervals for the maximum of the Youden index and the corresponding cutoff point of a continuous biomarker
Abstract Evaluation of the overall accuracy of biomarkers might be based on average
measures of the sensitivity for all possible specificities‐and vice versa‐or equivalently the …
measures of the sensitivity for all possible specificities‐and vice versa‐or equivalently the …
Rheostat functional outcomes occur when substitutions are introduced at nonconserved positions that diverge with speciation
L Swint‐Kruse, TA Martin, BM Page, T Wu… - Protein …, 2021 - Wiley Online Library
When amino acids vary during evolution, the outcome can be functionally neutral or
biologically‐important. We previously found that substituting a subset of nonconserved …
biologically‐important. We previously found that substituting a subset of nonconserved …
The New Zealand Parkinson's progression programme
ABSTRACT We describe the New Zealand Parkinson's Progression Programme (NZP3), its
goals, findings, and future plans. To date, 354 people with Parkinson's disease and 89 …
goals, findings, and future plans. To date, 354 people with Parkinson's disease and 89 …
The length of the receiver operating characteristic curve and the two cutoff Youden index within a robust framework for discovery, evaluation, and cutoff estimation in …
LE Bantis, JV Tsimikas, GR Chambers… - Statistics in …, 2021 - Wiley Online Library
During the early stage of biomarker discovery, high throughput technologies allow for
simultaneous input of thousands of biomarkers that attempt to discriminate between healthy …
simultaneous input of thousands of biomarkers that attempt to discriminate between healthy …
Estimation and construction of confidence intervals for biomarker cutoff‐points under the shortest Euclidean distance from the ROC surface to the perfection corner
BR Mosier, LE Bantis - Statistics in medicine, 2021 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive type of cancer with a 5‐year
survival rate of less than 5%. As in many other diseases, its diagnosis might involve …
survival rate of less than 5%. As in many other diseases, its diagnosis might involve …
Confidence intervals for differences between volumes under receiver operating characteristic surfaces (VUS) and generalized Youden indices (GYIs)
This article explores both existing and new methods for the construction of confidence
intervals for differences of indices of diagnostic accuracy of competing pairs of biomarkers in …
intervals for differences of indices of diagnostic accuracy of competing pairs of biomarkers in …
Evaluating joint confidence region of hypervolume under ROC manifold and generalized Youden index
In biomarker evaluation/diagnostic studies, the hypervolume under the receiver operating
characteristic manifold (HUM K HUM _K) and the generalized Youden index (JK J _K) are …
characteristic manifold (HUM K HUM _K) and the generalized Youden index (JK J _K) are …
A new accuracy metric under three classes when subclasses are involved and its confidence interval estimation
“Compound multi‐class classification” refers to the setting where three or more main classes
are involved and at least one of the main classes have multiple subclasses. A common …
are involved and at least one of the main classes have multiple subclasses. A common …
On optimal biomarker cutoffs accounting for misclassification costs in diagnostic trilemmas with applications to pancreatic cancer
LE Bantis, JV Tsimikas - Statistics in medicine, 2022 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is the most deadly cancer and currently there is
strong clinical interest in novel biomarkers that contribute to its early detection. Assessing …
strong clinical interest in novel biomarkers that contribute to its early detection. Assessing …