Comprehensive and critical view on the anti-inflammatory and immunomodulatory role of natural phenolic antioxidants

AM Pisoschi, F Iordache, L Stanca, C Cimpeanu… - European Journal of …, 2023 - Elsevier
The immune response encompasses innate and adaptive immunity, each with distinct and
specific activities. The innate immune system is constituted by phagocytic cells …

[HTML][HTML] Promising influences of hesperidin and hesperetin against diabetes and its complications: a systematic review of molecular, cellular, and metabolic effects

A Mirzaei, A Mirzaei, SN Khalilabad, VR Askari… - EXCLI …, 2023 - ncbi.nlm.nih.gov
Hesperidin and hesperetin, two flavonoids with potential therapeutic value, have been
extensively studied in the context of diabetes management. The main objective of this …

Mitigation of BMP-induced inflammation in craniofacial bone regeneration and improvement of bone parameters by dietary hesperidin

PA Miguez, V de Paiva Gonçalves, ML Musskopf… - Scientific Reports, 2024 - nature.com
Based on anti-inflammatory and osteogenic properties of hesperidin (HE), we hypothesized
its systemic administration could be a cost-effective method of improving BMP-induced bone …

[HTML][HTML] Dietary Polyphenols and Gut Microbiota Cross-Talk: Molecular and Therapeutic Perspectives for Cardiometabolic Disease: A Narrative Review

R Cano, V Bermúdez, N Galban, B Garrido… - International Journal of …, 2024 - mdpi.com
The intricate interplay between the gut microbiota and polyphenols has emerged as a
captivating frontier in understanding and potentially harnessing the therapeutic potential of …

Botany, phytochemistry, pharmacologic activities, traditional applications, pharmacokinetics, quality control and toxicity of Zanthoxyli Radix: an updated review

FH Luo, ZH Chen, FF Zeng, X Yang, JJ Li… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Zanthoxyli Radix (ZR), the dry root of
Zanthoxylum nitidum (Roxb.) DC (ZN) is known as Liang Mian Zhen in China and has been …

Hesperidin-loaded PVA/alginate hydrogel: targeting NFκB/iNOS/COX-2/TNF-α inflammatory signaling pathway

AS Kodous, MA Abdel-Maksoud, MA El-Tayeb… - Frontiers in …, 2024 - frontiersin.org
Introduction Skin injuries represent a prevalent form of physical trauma, necessitating
effective therapeutic strategies to expedite the wound healing process. Hesperidin, a …

Development of polyvinyl alcohol nanofiber scaffolds loaded with flaxseed extract for bone regeneration: phytochemicals, cell proliferation, adhesion, and osteogenic …

AG Abdelaziz, H Nageh, MS Abdalla, SM Abdo… - Frontiers in …, 2024 - frontiersin.org
Introduction: Bone tissue engineering seeks innovative materials that support cell growth
and regeneration. Electrospun nanofibers, with their high surface area and tunable …

Phytochemical Analysis and Antioxidant Effects of Prunella vulgaris in Experimental Acute Inflammation

CM Mîrza, TV Mîrza, ACM Odagiu, A Uifălean… - International Journal of …, 2024 - mdpi.com
Prunella vulgaris (PV) is one of the most commonly used nutraceuticals as it has been
proven to have anti-inflammatory and antioxidant properties. The aim of this study was to …

Hesperidin, a Potential Antiviral Agent against SARS-CoV-2: The Influence of Citrus Consumption on COVID-19 Incidence and Severity in China

A Kowalczyk - Medicina, 2024 - mdpi.com
This review examines hesperidin, a citrus bioflavonoid, as a potential antiviral agent against
SARS-CoV-2. The COVID-19 pandemic has demanded an urgent need to search for …

Research progress on the regulatory and pharmacological mechanism of chemical components of Dendrobium

X Wei, D Wang, Z Xu, J Liu, Q Zhu, Q Chen, H Tang… - Heliyon, 2024 - cell.com
Dendrobium is a precious Chinese herbal medicine, which belongs to the genus
Orchidaceae. Ancient records and modern pharmacological research show that …