Long COVID or post-COVID-19 condition: past, present and future research directions

C Fernández-de-Las-Peñas, AV Raveendran… - Microorganisms, 2023 - mdpi.com
The presence of symptoms after an acute SARS-CoV-2 infection (long-COVID) has become
a worldwide healthcare emergency but remains underestimated and undertreated due to a …

Exploring the complexities of long COVID

J Donald, SE Bilasy, C Yang, A El-Shamy - Viruses, 2024 - mdpi.com
Since the emergence of the SARS-CoV-2 virus in 2019, nearly 700 million COVID-19 cases
and 7 million deaths have been reported globally. Despite most individuals recovering …

Exploring the Influence of Gut–Brain Axis Modulation on Cognitive Health: A Comprehensive Review of Prebiotics, Probiotics, and Symbiotics

M Fekete, A Lehoczki, D Major, V Fazekas-Pongor… - Nutrients, 2024 - mdpi.com
Recent research exploring the relationship between the gut and the brain suggests that the
condition of the gut microbiota can influence cognitive health. A well-balanced gut …

Long COVID in Children, Adults, and Vulnerable Populations: A Comprehensive Overview for an Integrated Approach

V Calcaterra, S Zanelli, A Foppiani, E Verduci… - Diseases, 2024 - mdpi.com
Long COVID affects both children and adults, including subjects who experienced severe,
mild, or even asymptomatic SARS-CoV-2 infection. We have provided a comprehensive …

Gut microbe–host interactions in post-COVID syndrome: a debilitating or restorative partnership?

TPM Scheithauer, RC Montijn, A Mieremet - Gut Microbes, 2024 - Taylor & Francis
Post-COVID syndrome (PCS) patients have reported a wide range of symptoms, including
fatigue, shortness of breath, and diarrhea. Particularly, the presence of gastrointestinal …

COVID-19-associated encephalopathy: connection between neuroinflammation and microbiota-gut-brain axis

K Duve, P Petakh, O Kamyshnyi - Frontiers in Microbiology, 2024 - frontiersin.org
While neurological complications of COVID-19, such as encephalopathy, are relatively rare,
their potential significant impact on long-term morbidity is substantial, especially given the …

[HTML][HTML] Diffusion magnetic resonance spectroscopy captures microglial reactivity related to gut-derived systemic lipopolysaccharide: A preliminary study

A Birg, HJ van der Horn, SG Ryman, F Branzoli… - Brain, Behavior, and …, 2024 - Elsevier
Neuroinflammation is a key component underlying multiple neurological disorders, yet non-
invasive and cost-effective assessment of in vivo neuroinflammatory processes in the central …

[HTML][HTML] Mechanisms of Gut-Related Viral Persistence in Long COVID

P McMillan, AJ Turner, BD Uhal - Viruses, 2024 - mdpi.com
Long COVID (post-acute sequelae of COVID-19—PASC) is a consequence of infection by
SARS-CoV-2 that continues to disrupt the well-being of millions of affected individuals for …

Neurovascular coupling impairment as a mechanism for cognitive deficits in COVID-19

CD Owens, C Bonin Pinto, S Detwiler… - Brain …, 2024 - academic.oup.com
Components that comprise our brain parenchymal and cerebrovascular structures provide a
homeostatic environment for proper neuronal function to ensure normal cognition. Cerebral …

Hippocampal region metabolites and cognitive impairment in patients with general paresis: based on 1H-proton magnetic resonance spectroscopy

X Che, T Miao, H Shi, Z Li, Y Ning - Frontiers in Pharmacology, 2024 - frontiersin.org
Background: This study utilizes Hydrogen proton magnetic resonance spectroscopy (1H-
MRS) to investigate metabolite concentrations in the bilateral hippocampus of general …