Scaffolding in tissue engineering: general approaches and tissue-specific considerations

BP Chan, KW Leong - European spine journal, 2008 - Springer
Scaffolds represent important components for tissue engineering. However, researchers
often encounter an enormous variety of choices when selecting scaffolds for tissue …

Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its …

JC Iatridis, SB Nicoll, AJ Michalek, BA Walter… - The spine journal, 2013 - Elsevier
BACKGROUND CONTEXT: Degeneration and injuries of the intervertebral disc (IVD) result
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …

Single lamellar mechanics of the human lumbar anulus fibrosus

GA Holzapfel, CAJ Schulze-Bauer, G Feigl… - … and modeling in …, 2005 - Springer
The mechanical behavior of the entire anulus fibrosus is determined essentially by the
tensile properties of its lamellae, their fiber orientations, and the regional variation of these …

Spine biomechanics

MA Adams, P Dolan - Journal of biomechanics, 2005 - Elsevier
Current trends in spine research are reviewed in order to suggest future opportunities for
biomechanics. Recent studies show that psychosocial factors influence back pain behaviour …

Mechanical design criteria for intervertebral disc tissue engineering

NL Nerurkar, DM Elliott, RL Mauck - Journal of biomechanics, 2010 - Elsevier
Due to the inability of current clinical practices to restore function to degenerated
intervertebral discs, the arena of disc tissue engineering has received substantial attention …

Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: potential and limitations for stem cell therapy in disc regeneration

D Sakai, J Mochida, T Iwashina, T Watanabe, T Nakai… - Spine, 2005 - journals.lww.com
Study Design. An in vivo study to assess the differentiation status of mesenchymal stem cells
(MSCs) transplanted to the nucleus pulposus of degenerative discs in a rabbit model …

[HTML][HTML] Challenges and strategies in the repair of ruptured annulus fibrosus

CC Guterl, EY See, SBG Blanquer… - European cells & …, 2013 - ncbi.nlm.nih.gov
Lumbar discectomy is the surgical procedure most frequently performed for patients
suffering from low back pain and sciatica. Disc herniation as a consequence of degenerative …

[图书][B] Scaffolding in tissue engineering

PX Ma, J Elisseeff - 2005 - taylorfrancis.com
The growing interest in scaffolding design and increasing research programs dedicated to
regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While …

Injectable oxidized hyaluronic acid/adipic acid dihydrazide hydrogel for nucleus pulposus regeneration

WY Su, YC Chen, FH Lin - Acta biomaterialia, 2010 - Elsevier
Injectable hydrogel allows irregular surgical defects to be completely filled, lessens the risk
of implant migration, and minimizes surgical defects due to the solution–gel state …

Transplantation of mesenchymal stem cells in a canine disc degeneration model

A Hiyama, J Mochida, T Iwashina, H Omi… - Journal of …, 2008 - Wiley Online Library
Transplantation of mesenchymal stem cells (MSCs) is effective in decelerating disc
degeneration in small animals; much remains unknown about this new therapy in larger …