Since the elucidation of the molecular structure of nucleic acids and understanding of their
role in encoding and translating genetic information into biological function, 1 the knowledge …

Gene therapy using nucleic acids has many clinical applications for the treatment of
diseases with a genetic origin as well as for the development of innovative vaccine …

Polymeric nanoparticles-based therapeutics show great promise in the treatment of a wide
range of diseases, due to the flexibility in which their structures can be modified, with …

Near-infrared light-responsive inorganic nanoparticles have been shown to enhance the
efficacy of cancer photothermal ablation therapy. However, current nanoparticle-mediated …

Chitosan (CS) is one of the most functional natural biopolymer widely used in the
pharmaceutical field due to its biocompatibility and biodegradability. These privileges lead …

Gene transfer methods are promising in the field of gene therapy. Current methods for gene
transfer include three major groups: viral, physical and chemical methods. This review …

Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

Investigation of the physiological and pathological functions of formaldehyde (FA) are
largely restricted by a lack of useful FA imaging agents, in particular, those that allow …

Chitosan is a linear polysaccharide composed of randomly distributed β-(1-4)-linked d-
glucosamine and N-acetyl-d-glucosamine. It is one of the major cationic polymers and the …

Among non-viral vectors, chitosan and chitosan derivatives have been developed in vitro
and in vivo for DNA and siRNA delivery systems because of their cationic charge …