[HTML][HTML] Association of diabetes mellitus and alcohol abuse with cancer: Molecular mechanisms and clinical significance
BQ Lam, R Srivastava, J Morvant, S Shankar… - Cells, 2021 - mdpi.com
Diabetes mellitus (DM), one of the metabolic diseases which is characterized by sustained
hyperglycemia, is a life-threatening disease. The global prevalence of DM is on the rise …
hyperglycemia, is a life-threatening disease. The global prevalence of DM is on the rise …
[HTML][HTML] Expanding telmisartan's therapeutic horizon: exploring its multifaceted mechanisms beyond cardiovascular disorders
YS Ahire, VA Bairagi, DB Somavanshi… - Future Journal of …, 2024 - Springer
Background Telmisartan, a potent angiotensin II type-1 receptor blocker as well as partial
PPAR–gamma agonist, has emerged as a versatile therapeutic agent with diverse …
PPAR–gamma agonist, has emerged as a versatile therapeutic agent with diverse …
Genistein ameliorates cardiac inflammation and oxidative stress in streptozotocin-induced diabetic cardiomyopathy in rats
SK Gupta, S Dongare, R Mathur, IR Mohanty… - Molecular and cellular …, 2015 - Springer
The present study was undertaken to evaluate the protective effects of genistein against
cardiac inflammation and oxidative stress in streptozotocin (STZ)(45 mg/kg body weight) …
cardiac inflammation and oxidative stress in streptozotocin (STZ)(45 mg/kg body weight) …
Benzyl isothiocyanates modulate inflammation, oxidative stress, and apoptosis via Nrf2/HO-1 and NF-κB signaling pathways on indomethacin-induced gastric injury in …
SA El Badawy, HA Ogaly, RM Abd-Elsalam… - Food & Function, 2021 - pubs.rsc.org
The present study investigated the gastroprotective activity of benzyl isothiocyanates (BITC)
on indomethacin (IND)-induced gastric injury in a rat model and explicated the possible …
on indomethacin (IND)-induced gastric injury in a rat model and explicated the possible …
Attenuating effect of lisinopril and telmisartan in intracerebroventricular streptozotocin induced experimental dementia of Alzheimer's disease type: possible …
This study investigates the beneficial role of lisinopril, an angiotensin converting enzyme
inhibitor (ACEI) and telmisartan, an angiotensin receptor blocker (ARB), in …
inhibitor (ACEI) and telmisartan, an angiotensin receptor blocker (ARB), in …
[HTML][HTML] A novel role of irbesartan in gastroprotection against indomethacin-induced gastric injury in rats: targeting DDAH/ADMA and EGFR/ERK signaling
NN Shahin, NF Abdelkader, MM Safar - Scientific reports, 2018 - nature.com
The advent of angiotensin II type 1 receptor blockers (ARBs) as intriguing gastroprotective
candidates and the superior pharmacokinetics and pharmacodynamics displayed by …
candidates and the superior pharmacokinetics and pharmacodynamics displayed by …
Hesperidin protects against stress induced gastric ulcer through regulation of peroxisome proliferator activator receptor gamma in diabetic rats
SM Elshazly, DM Abd El Motteleb… - Chemico-biological …, 2018 - Elsevier
Stress induced gastric ulcer is a serious health problem in diabetic patients. Some studies
reported that hesperidin (HDN), a citrus bioflavonoid, can bind to and stimulate peroxisome …
reported that hesperidin (HDN), a citrus bioflavonoid, can bind to and stimulate peroxisome …
[HTML][HTML] Zingiber officinale attenuates retinal microvascular changes in diabetic rats via anti-inflammatory and antiangiogenic mechanisms
S Dongare, SK Gupta, R Mathur, R Saxena… - Molecular …, 2016 - ncbi.nlm.nih.gov
Purpose Diabetic retinopathy is a common microvascular complication of long-standing
diabetes. Several complex interconnecting biochemical pathways are activated in response …
diabetes. Several complex interconnecting biochemical pathways are activated in response …
[HTML][HTML] In silico evaluation of ibuprofen and two benzoylpropionic acid derivatives with potential anti-inflammatory activity
JAHM Bittencourt, MFA Neto, PS Lacerda… - Molecules, 2019 - mdpi.com
Inflammation is a complex reaction involving cellular and molecular components and an
unspecific response to a specific aggression. The use of scientific and technological …
unspecific response to a specific aggression. The use of scientific and technological …
Inhibiting renin angiotensin system in rate limiting step by aliskiren as a new approach for preventing indomethacin induced gastric ulcers
Purpose Previously blocking the renin angiotensin system (RAAS) has been effective in the
prevention of gastric damage. Therefore, the aim of this study was to investigate the effects …
prevention of gastric damage. Therefore, the aim of this study was to investigate the effects …