Pathogenesis and current treatment strategies of hepatocellular carcinoma
D Tümen, P Heumann, K Gülow, CN Demirci… - Biomedicines, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the most frequent liver cancer with high lethality and low
five-year survival rates leading to a substantial worldwide burden for healthcare systems …
five-year survival rates leading to a substantial worldwide burden for healthcare systems …
Immunotherapies for hepatocellular carcinoma
JKH Liu, AF Irvine, RL Jones, A Samson - Cancer Medicine, 2022 - Wiley Online Library
Cases of hepatocellular carcinoma (HCC) are rapidly rising. This is particularly the case in
the Western world, as a result of increasing rates of chronic liver disease, secondary to …
the Western world, as a result of increasing rates of chronic liver disease, secondary to …
Selenium nanoparticles overcomes sorafenib resistance in thioacetamide induced hepatocellular carcinoma in rats by modulation of mTOR, NF-κB pathways and …
TM Al-Noshokaty, NM Mesbah, DM Abo-Elmatty… - Life Sciences, 2022 - Elsevier
Aims The first-line treatment for advanced hepatocellular carcinoma (HCC) is the
multikinase inhibitor sorafenib (SOR). Sofafenib resistance is linked to protein kinase …
multikinase inhibitor sorafenib (SOR). Sofafenib resistance is linked to protein kinase …
Combining crocin and sorafenib improves their tumor-inhibiting effects in a rat model of diethylnitrosamine-induced cirrhotic-hepatocellular carcinoma
Simple Summary Liver cancer represents one of the most lethal forms of cancer, with
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …
Recent updates on viral Oncogenesis: Available preventive and therapeutic entities
Human viral oncogenesis is a complex phenomenon and a major contributor to the global
cancer burden. Several recent findings revealed cellular and molecular pathways that …
cancer burden. Several recent findings revealed cellular and molecular pathways that …
MEX3C-mediated decay of SOCS3 mRNA promotes JAK2/STAT3 signaling to facilitate metastasis in hepatocellular carcinoma
Y Xiao, Y Li, D Shi, X Wang, S Dai, M Yang, L Kong… - Cancer Research, 2022 - AACR
Tumor metastasis is one of the major causes of high mortality in patients with hepatocellular
carcinoma (HCC). Sustained activation of STAT3 signaling plays a critical role in HCC …
carcinoma (HCC). Sustained activation of STAT3 signaling plays a critical role in HCC …
Role of exosomal microRNAs in cancer therapy and drug resistance mechanisms: focus on hepatocellular carcinoma
V Zelli, C Compagnoni, R Capelli, A Corrente… - Frontiers in …, 2022 - frontiersin.org
Extracellular vesicles (EVs), defined as intercellular messengers that carry their cargos
between cells, are involved in several physiological and pathological processes. These …
between cells, are involved in several physiological and pathological processes. These …
Immune signature-based hepatocellular carcinoma subtypes may provide novel insights into therapy and prognosis predictions
Q Zheng, Q Yang, J Zhou, X Gu, H Zhou, X Dong… - Cancer cell …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) has a poor prognosis and has become the
sixth most common malignancy worldwide due to its high incidence. Advanced approaches …
sixth most common malignancy worldwide due to its high incidence. Advanced approaches …
The involvement of ROS-regulated programmed cell death in hepatocellular carcinoma
H Cai, Z Meng, F Yu - Critical Reviews in Oncology/Hematology, 2024 - Elsevier
Reactive oxidative species (ROS) is a crucial factor in the regulation of cellular biological
activity and function, and aberrant levels of ROS can contribute to the development of a …
activity and function, and aberrant levels of ROS can contribute to the development of a …
[HTML][HTML] Current therapeutic modalities and chemopreventive role of natural products in liver cancer: Progress and promise
Liver cancer is a severe concern for public health officials since the clinical cases are
increasing each year, with an estimated 5-year survival rate of 30%–35% after diagnosis …
increasing each year, with an estimated 5-year survival rate of 30%–35% after diagnosis …