Current understanding of the therapeutic benefits of mesenchymal stem cells in acute respiratory distress syndrome
M Lopes-Pacheco, C Robba, PRM Rocco… - Cell biology and …, 2020 - Springer
The acute respiratory distress syndrome (ARDS) is a multifaceted lung disorder in which no
specific therapeutic intervention is able to effectively improve clinical outcomes. Despite an …
specific therapeutic intervention is able to effectively improve clinical outcomes. Despite an …
[HTML][HTML] Cell therapy in acute respiratory distress syndrome
S Horie, HE Gonzalez, JG Laffey… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
Acute respiratory distress syndrome (ARDS) is driven by a severe pro-inflammatory
response resulting in lung damage, impaired gas exchange and severe respiratory failure …
response resulting in lung damage, impaired gas exchange and severe respiratory failure …
Leukocyte inclusion within a platelet rich plasma-derived fibrin scaffold stimulates a more pro-inflammatory environment and alters fibrin properties
One of the main differences among platelet-rich plasma (PRP) products is the inclusion of
leukocytes that may affect the biological efficacy of these autologous preparations. The …
leukocytes that may affect the biological efficacy of these autologous preparations. The …
Prospects for translational regenerative medicine
Translational medicine is an evolutional concept that encompasses the rapid translation of
basic research for use in clinical disease diagnosis, prevention and treatment. It follows the …
basic research for use in clinical disease diagnosis, prevention and treatment. It follows the …
Approaches to in vitro tissue regeneration with application for human disease modeling and drug development
MR Ebrahimkhani, CL Young, DA Lauffenburger… - Drug discovery today, 2014 - Elsevier
Highlights•Reliable in vitro models for human disease are needed.•Human cell-based
models including iPS cell-based models are emerging.•Biomimetic matrices and substrates …
models including iPS cell-based models are emerging.•Biomimetic matrices and substrates …
[HTML][HTML] Uncertainty and innovation: Understanding the role of cell-based manufacturing facilities in shaping regulatory and commercialization environments
R Isasi, V Rahimzadeh, K Charlebois - Applied & translational genomics, 2016 - Elsevier
The purpose of this qualitative study is to elucidate stakeholder perceptions of, and
institutional practices related to cell-based therapies and products (CTP) regulation and …
institutional practices related to cell-based therapies and products (CTP) regulation and …
Biomaterials in regenerative medicine: Challenges in technology transfer from science to process development
P Chandra, JJ Yoo, SJ Lee - Translational Regenerative Medicine, 2015 - Elsevier
Biomaterials have substantial value in tissue engineering and regenerative medicine, but
translating advances in biomaterials science into products with clinical applications involves …
translating advances in biomaterials science into products with clinical applications involves …
Regenerative urology clinical trials: an ethical assessment of road blocks and solutions
AJM Oerlemans, WFJ Feitz, E van Leeuwen… - … Engineering Part B …, 2013 - liebertpub.com
Tissue engineering—part of regenerative medicine—is a promising technology that could
potentially offer elegant solutions to urogenital defects, but so far, it has fallen short of its …
potentially offer elegant solutions to urogenital defects, but so far, it has fallen short of its …
Regenerative Medicine in South Korea: bridging the gap between authorization and reimbursement
DS Kim, G Lee, H Cho, SJ Bae - Frontiers in bioengineering and …, 2021 - frontiersin.org
Regenerative medicine (RM) has considerable potential to address the needs of aging-
related and uncurable diseases. However, its incorporation into reimbursement of health …
related and uncurable diseases. However, its incorporation into reimbursement of health …
Regenerative medicine and responsible research and innovation: proposals for a responsible acceleration to the clinic
A Webster - Regenerative Medicine, 2017 - Taylor & Francis
This paper asks how regenerative medicine can be examined through the 'responsible
research and innovation'(RRI) approach which has been developed over the past decade. It …
research and innovation'(RRI) approach which has been developed over the past decade. It …