[HTML][HTML] Synthesis methods of 1, 2, 3-/1, 2, 4-triazoles: A review

J Dai, S Tian, X Yang, Z Liu - Frontiers in Chemistry, 2022 - frontiersin.org
Triazole, comprising three nitrogen atoms and two carbon atoms, is divided into two isomers
1, 2, 3-triazole and 1, 2, 4-triazole. Compounds containing a triazole are one of the …

[HTML][HTML] Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review

M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …

In vitro and in silico exploration of newly synthesized triazolyl- isonicotinohydrazides as potent antitubercular agents

RD Bakale, PS Phatak, SS Rathod… - Journal of …, 2023 - Taylor & Francis
In the present study, we have reported the synthesis of novel isoniazid-triazole derivatives
(4a-r), via the click chemistry approach. The synthesized isoniazid-triazole derivatives have …

N-Heterocyclic imino-catalyzed 1, 4-regioselective azide–alkyne cycloaddition (AAC): a metal-free approach

S Revathi, AL Shinde, MK Rajashekhar… - Chemical …, 2023 - pubs.rsc.org
An unprecedented synthetic approach has been devised to efficiently synthesize
regioselective 1, 4-disubstituted 1, 2, 3-triazoles. This technique relies on the use of …

Design, Synthesis, and Biological Activity Evaluation of Novel AZT and Adenosine‐Derived 1, 2, 3‐Triazoles

DA Le, NH Truong, VD Vu, TH Doan, MT Le… - Journal of …, 2023 - Wiley Online Library
CuSO4/hydrazine hydrate was used as a catalyst system for copper (I)‐catalyzed alkyne‐
azide cycloaddition (CuAAC) of AZT and 5′‐azido adenosine with terminal alkynes to give …

Investigation of new 1,2,3-triazolyl-quinolinyl-propan-2-ol derivatives as potential antimicrobial agents: in vitro and in silico approach

AD Shinde, YM Nandurkar, S Bhalekar… - Journal of …, 2024 - Taylor & Francis
Abstract A new series of 1-((1-(4-substituted benzyl)-1 H-1, 2, 3-triazol-4-yl) methoxy)-2-(2-
substituted quinolin-4-yl) propan-2-ol (9a-x) have been synthesized. The newly synthesized …

Recent progress on synthesis of functionalized 1, 5-disubstituted triazoles

MK Jaiswal, A Gupta, FJ Ansari… - Current Organic …, 2024 - ingentaconnect.com
Immediately after the invention of 'Click Chemistry'in 2002, the regioselective 1, 2, 3-triazole
scaffolds resulted from respective organic azides and terminal alkynes under Cu (I) catalysis …

Design, synthesis, and biological evaluation of 1, 2, 4-triazole derivatives as potent antitubercular agents

Y Wen, S Lun, Y Jiao, W Zhang, T Hu, T Liu… - Chinese Chemical …, 2024 - Elsevier
Inhibition of mycobacterial membrane protein large 3 (MmpL3) thereby affecting the mycolic
acid biosynthetic pathway has been proven to be an effective strategy for developing …

Organocatalyzed Regioselective Synthesis of 1, 5‐Disubstituted 1, 2, 3‐Triazolyl Glycoconjugates

MK Jaiswal, A Gupta, MS Yadav… - … A European Journal, 2023 - Wiley Online Library
Abstract A novel organocatalyzed [3+ 2] cycloaddition reaction of nitroolefins with glycosyl
azides as well as organic azides has been developed for successful construction of 1, 5 …

Growing Impact of Intramolecular Click Chemistry in Organic Synthesis

MK Jaiswal, VK Tiwari - The Chemical Record, 2023 - Wiley Online Library
Click Chemistry, a modular, rapid, and one of the most reliable tool for the regioselective 1,
2, 3‐triazole forming [3+ 2] reaction of organic azide and terimal alkyne is widely explored in …