Achilles and patellar tendinopathy loading programmes: a systematic review comparing clinical outcomes and identifying potential mechanisms for effectiveness

P Malliaras, CJ Barton, ND Reeves, H Langberg - Sports medicine, 2013 - Springer
Introduction Achilles and patellar tendinopathy are overuse injuries that are common among
athletes. Isolated eccentric muscle training has become the dominant conservative …

Tendon injuries: Basic science and new repair proposals

F Wu, M Nerlich, D Docheva - EFORT open reviews, 2017 - eor.bioscientifica.com
Tendons connect muscles to bones, ensuring joint movement. With advanced age, tendons
become more prone to degeneration followed by injuries. Tendon repair often requires …

Pathogenesis of tendinopathies: inflammation or degeneration?

M Abate, K Gravare Silbernagel, C Siljeholm… - Arthritis research & …, 2009 - Springer
The intrinsic pathogenetic mechanisms of tendinopathies are largely unknown and whether
inflammation or degeneration has the prominent role is still a matter of debate. Assuming …

The pain of tendinopathy: physiological or pathophysiological?

E Rio, L Moseley, C Purdam, T Samiric, D Kidgell… - Sports medicine, 2014 - Springer
Tendon pain remains an enigma. Many clinical features are consistent with tissue disruption—
the pain is localised, persistent and specifically associated with tendon loading, whereas …

Tendinopathy: injury, repair, and current exploration

K Lipman, C Wang, K Ting, C Soo… - … design, development and …, 2018 - Taylor & Francis
Both acute and chronic tendinopathy result in high morbidity, requiring management that is
often lengthy and expensive. However, limited and conflicting scientific evidence …

Novel approaches for the management of tendinopathy

N Maffulli, UG Longo, V Denaro - JBJS, 2010 - journals.lww.com
➤ Eccentric exercises have been proposed to promote collagen fiber cross-link formation
within the tendon, thereby facilitating tendon remodeling. Overall results suggest a trend for …

The pathogenesis of Achilles tendinopathy: a systematic review

B Magnan, M Bondi, S Pierantoni, E Samaila - Foot and Ankle Surgery, 2014 - Elsevier
Achilles tendinopathy is a degenerative, not an inflammatory, condition. It is prevalent in
athletes involved in running sports. A systematic literature review on Achilles tendon …

What are the validated animal models for tendinopathy?

PPY Lui, N Maffulli, C Rolf… - Scandinavian journal of …, 2011 - Wiley Online Library
Chronic tendinopathy refers to a broad spectrum of pathological conditions in tendons and
their insertion, with symptoms including activity‐related chronic pain. To study the …

Tendinopathy in sport

PW Ackermann, P Renström - Sports health, 2012 - journals.sagepub.com
Context: Tendinopathy is increasing in prevalence and accounts for a substantial part of all
sports injuries and occupational disorders. Despite the magnitude of the disorder, high …

The mechanism for efficacy of eccentric loading in Achilles tendon injury; an in vivo study in humans

JD Rees, GA Lichtwark, RL Wolman… - Rheumatology, 2008 - academic.oup.com
Objective. Degenerative disorders of tendons present an enormous clinical challenge. They
are extremely common, prone to recur and existing medical and surgical treatments are …