[HTML][HTML] How genomics can help biodiversity conservation
The availability of public genomic resources can greatly assist biodiversity assessment,
conservation, and restoration efforts by providing evidence for scientifically informed …
conservation, and restoration efforts by providing evidence for scientifically informed …
[HTML][HTML] The era of reference genomes in conservation genomics
Progress in genome sequencing now enables the large-scale generation of reference
genomes. Various international initiatives aim to generate reference genomes representing …
genomes. Various international initiatives aim to generate reference genomes representing …
Building pangenome graphs
Pangenome graphs can represent all variation between multiple reference genomes, but
current approaches to build them exclude complex sequences or are based upon a single …
current approaches to build them exclude complex sequences or are based upon a single …
The design and construction of reference pangenome graphs with minigraph
The recent advances in sequencing technologies enable the assembly of individual
genomes to the quality of the reference genome. How to integrate multiple genomes from …
genomes to the quality of the reference genome. How to integrate multiple genomes from …
Graph-based pan-genomes: increased opportunities in plant genomics
S Wang, YQ Qian, RP Zhao, LL Chen… - Journal of …, 2023 - academic.oup.com
Due to the development of sequencing technology and the great reduction in sequencing
costs, an increasing number of plant genomes have been assembled, and numerous …
costs, an increasing number of plant genomes have been assembled, and numerous …
A diploid assembly-based benchmark for variants in the major histocompatibility complex
Most human genomes are characterized by aligning individual reads to the reference
genome, but accurate long reads and linked reads now enable us to construct accurate …
genome, but accurate long reads and linked reads now enable us to construct accurate …
Are we there yet? Driving the road to evolutionary graph-pangenomics
S Hübner - Current Opinion in Plant Biology, 2022 - Elsevier
With increase in the number of sequenced genomes, it is now recognized that graph-based
pangenomes can provide a comprehensive platform to study diversity in a population or …
pangenomes can provide a comprehensive platform to study diversity in a population or …
The Practical Haplotype Graph, a platform for storing and using pangenomes for imputation
PJ Bradbury, T Casstevens, SE Jensen… - …, 2022 - academic.oup.com
Motivation Pangenomes provide novel insights for population and quantitative genetics,
genomics and breeding not available from studying a single reference genome. Instead, a …
genomics and breeding not available from studying a single reference genome. Instead, a …
Whole‐genome sequencing and genome regions of special interest: Lessons from major histocompatibility complex, sex determination, and plant self‐incompatibility
Whole‐genome sequencing of non‐model organisms is now widely accessible and has
allowed a range of questions in the field of molecular ecology to be investigated with greater …
allowed a range of questions in the field of molecular ecology to be investigated with greater …
Haplotype-aware variant selection for genome graphs
Graph-based genome representations have proven to be a powerful tool in genomic
analysis due to their ability to encode variations found in multiple haplotypes and capture …
analysis due to their ability to encode variations found in multiple haplotypes and capture …