Inflammation contributes to the pathogenesis of most acute and chronic liver diseases.
Inflammasomes are multiprotein complexes that can sense danger signals from damaged …

Various stress factors leading to protein damage induce the activation of an evolutionarily
conserved cell protective mechanism, the heat shock response (HSR), to maintain protein …

Liver dysfunction is strongly associated with poor survival of sepsis patients. Cytosolic
lipopolysaccharide (LPS) sensing by Caspase-4/5/11 for pyroptosis activation is a major …

Heat shock transcription factor 1 (HSF1) has been implicated in the differential regulation of
cell stress and disease states. β‐catenin activation is essential for immune homeostasis …

Cardiovascular disease is the result of complicated pathophysiological processes in the
tissues that make up the blood vessels and heart. Heat shock protein 90 (HSP90) can …

Introduction: Alzheimer's disease, characterized by the accumulation of
hyperphosphorylated tau and β amyloid (Aβ), currently lacks effective treatment. Chaperone …

Aims: Emodin is an anthraquinone with potential anti-inflammatory properties. However, the
possible molecular mechanisms and protective effects of emodin are not clear. The objective …

Lung cancer is one of the most common malignant cancers worldwide. Searching for
specific cancer targets and developing efficient therapies with lower toxicity is urgently …

Sterile inflammation is initiated by damage-associated molecular patterns (DAMPs) and a
key contributor to acute liver injury (ALI). However, the current knowledge on those DAMPs …

The microalgae are an important source of bioactive molecules including β-glucans that can
be used as immunostimulants in aquaculture. In the present study, the antioxidant capacity …