[HTML][HTML] Chitosan: a potential biopolymer in drug delivery and biomedical applications

N Desai, D Rana, S Salave, R Gupta, P Patel… - Pharmaceutics, 2023 - mdpi.com
Chitosan, a biocompatible and biodegradable polysaccharide derived from chitin, has
surfaced as a material of promise for drug delivery and biomedical applications. Different …

[HTML][HTML] Factors influencing the antibacterial activity of chitosan and chitosan modified by functionalization

C Ardean, CM Davidescu, NS Nemeş… - International Journal of …, 2021 - mdpi.com
The biomedical and therapeutic importance of chitosan and chitosan derivatives is the
subject of interdisciplinary research. In this analysis, we intended to consolidate some of the …

Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases

M Mehta, D Tewari, G Gupta, R Awasthi, H Singh… - Chemico-biological …, 2019 - Elsevier
Oligonucleotide-based therapies are advanced novel interventions used in the management
of various respiratory diseases such as asthma and Chronic Obstructive Pulmonary Disease …

[HTML][HTML] Chitosan as a wound dressing starting material: Antimicrobial properties and mode of action

MA Matica, FL Aachmann, A Tøndervik… - International journal of …, 2019 - mdpi.com
Fighting bacterial resistance is one of the concerns in modern days, as antibiotics remain the
main resource of bacterial control. Data shows that for every antibiotic developed, there is a …

[HTML][HTML] Recent advances in chitosan-based carriers for gene delivery

Y Cao, YF Tan, YS Wong, MWJ Liew, S Venkatraman - Marine drugs, 2019 - mdpi.com
Approximately 4000 diseases are associated with malfunctioning genes in a particular cell
type. Gene-based therapy provides a platform to modify the disease-causing genes …

Biomedical application of chitosan-based nanoscale delivery systems: Potential usefulness in siRNA delivery for cancer therapy

M Ashrafizadeh, M Delfi, F Hashemi, A Zabolian… - Carbohydrate …, 2021 - Elsevier
Gene therapy is an emerging and promising strategy in cancer therapy where small
interfering RNA (siRNA) system has been deployed for down-regulation of targeted gene …

Chitosan-based colloidal polyelectrolyte complexes for drug delivery: a review

D Wu, L Zhu, Y Li, X Zhang, S Xu, G Yang… - Carbohydrate polymers, 2020 - Elsevier
Polyelectrolyte complexes (PECs) as safe drug delivery carriers, are spontaneously formed
by mixing the oppositely charged polyelectrolyte solutions in water without using organic …

Chitosan—A versatile semi-synthetic polymer in biomedical applications

M Dash, F Chiellini, RM Ottenbrite, E Chiellini - Progress in polymer science, 2011 - Elsevier
This review outlines the new developments on chitosan-based bioapplications. Over the last
decade, functional biomaterials research has developed new drug delivery systems and …

Therapeutic targeting of non-coding RNAs in cancer

O Slaby, R Laga, O Sedlacek - Biochemical journal, 2017 - portlandpress.com
The majority of the human genome encodes RNAs that do not code for proteins. These non-
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …

Polysaccharides-based nanoparticles as drug delivery systems

Z Liu, Y Jiao, Y Wang, C Zhou, Z Zhang - Advanced drug delivery reviews, 2008 - Elsevier
Natural polysaccharides, due to their outstanding merits, have received more and more
attention in the field of drug delivery systems. In particular, polysaccharides seem to be the …