Recent progress on performance-enhancing strategies in flexible photodetectors: From structural engineering to flexible integration
As an important component of future electronic devices, photodetectors require mechanical
flexibility, and stretchability to meet the demands of conformal, portable, and lightweight …
flexibility, and stretchability to meet the demands of conformal, portable, and lightweight …
[HTML][HTML] Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in Parkinson's disease
The degeneration of mesencephalic dopaminergic neurons that innervate the basal ganglia
is responsible for the cardinal motor symptoms of Parkinson's disease (PD). It has been …
is responsible for the cardinal motor symptoms of Parkinson's disease (PD). It has been …
[HTML][HTML] Preserved neural dynamics across animals performing similar behaviour
Animals of the same species exhibit similar behaviours that are advantageously adapted to
their body and environment. These behaviours are shaped at the species level by selection …
their body and environment. These behaviours are shaped at the species level by selection …
[HTML][HTML] Early deficits in an in vitro striatal microcircuit model carrying the Parkinson's GBA-N370S mutation
Understanding medium spiny neuron (MSN) physiology is essential to understand motor
impairments in Parkinson's disease (PD) given the architecture of the basal ganglia. Here …
impairments in Parkinson's disease (PD) given the architecture of the basal ganglia. Here …
Preserved neural population dynamics across animals performing similar behaviour
Animals of the same species often exhibit similar behaviours that are advantageously
adapted to their body and their environment. These behaviours are shaped by selection …
adapted to their body and their environment. These behaviours are shaped by selection …
[HTML][HTML] Segregation of D1 and D2 dopamine receptors in the striatal direct and indirect pathways: An historical perspective
CR Gerfen - Frontiers in Synaptic Neuroscience, 2023 - frontiersin.org
The direct and indirect striatal pathways form a cornerstone of the circuits of the basal
ganglia. Dopamine has opponent affects on the function of these pathways due to the …
ganglia. Dopamine has opponent affects on the function of these pathways due to the …
[HTML][HTML] Multi-timescale reinforcement learning in the brain
To thrive in complex environments, animals and artificial agents must learn to act adaptively
to maximize fitness and rewards. Such adaptive behavior can be learned through …
to maximize fitness and rewards. Such adaptive behavior can be learned through …
Using temperature to analyze the neural basis of a time-based decision
The basal ganglia are thought to contribute to decision-making and motor control. These
functions are critically dependent on timing information, which can be extracted from the …
functions are critically dependent on timing information, which can be extracted from the …
[HTML][HTML] Electrophysiological insights into deep brain stimulation of the network disorder dystonia
D Franz, A Richter, R Köhling - Pflügers Archiv-European Journal of …, 2023 - Springer
Deep brain stimulation (DBS), a treatment for modulating the abnormal central neuronal
circuitry, has become the standard of care nowadays and is sometimes the only option to …
circuitry, has become the standard of care nowadays and is sometimes the only option to …
Dopamine neurons encode a multidimensional probabilistic map of future reward
Learning to predict rewards is a fundamental driver of adaptive behavior. Midbrain
dopamine neurons (DANs) play a key role in such learning by signaling reward prediction …
dopamine neurons (DANs) play a key role in such learning by signaling reward prediction …