Novel multicomponent reactions via trapping of protic onium ylides with electrophiles

X Guo, W Hu - Accounts of Chemical Research, 2013 - ACS Publications
Multicomponent reactions (MCRs) are one-pot processes in which three or more starting
materials form a product that incorporates the structural features of each reagent. These …

Higher-order multicomponent reactions: beyond four reactants

S Brauch, SS van Berkel, B Westermann - Chemical Society Reviews, 2013 - pubs.rsc.org
Multicomponent reactions (MCRs) are by far the most successful class of reactions leading
to high structural diversity and molecular complexity through a single transformation. As part …

Multicomponent reactions for the synthesis of bioactive compounds: A review

CS Graebin, FV Ribeiro, KR Rogério… - Current Organic …, 2019 - ingentaconnect.com
Multicomponent reactions (MCRs) are composed of three or more reagents in which the final
product has all or most of the carbon atoms from its starting materials. These reactions …

Recent developments in isocyanide based multicomponent reactions in applied chemistry

A Dömling - Chemical reviews, 2006 - ACS Publications
Multicomponent reactions (MCRs) are generally defined as reactions where more than two
staring materials react to form a product, incorporating essentially all of the atoms of the …

Natural product synthesis using multicomponent reaction strategies

BB Toure, DG Hall - Chemical reviews, 2009 - ACS Publications
The preparation of urea by Wöhler constituted a landmark achievement in organic chemistry,
and it laid the ground for the early days of target-oriented organic synthesis. 1 Since then …

Multicomponent reactions in unconventional solvents: state of the art

Y Gu - Green Chemistry, 2012 - pubs.rsc.org
Simple and green synthetic procedures constitute an important goal in organic synthesis.
The combination of multicomponent reactions (MCRs) and unconventional solvents has …

Donor− Acceptor-Substituted cyclopropane derivatives and their application in organic synthesis

HU Reissig, R Zimmer - Chemical reviews, 2003 - ACS Publications
For quite some time cyclopropane derivatives have been more than laboratory curiosities,
but they are frequently employed as versatile building blocks in organic syntheses. 1 Apt …

Strategies for innovation in multicomponent reaction design

B Ganem - Accounts of chemical research, 2009 - ACS Publications
By generating structural complexity in a single step from three or more reactants,
multicomponent reactions (MCRs) make it possible to synthesize target compounds with …

Photochemical reactions as key steps in organic synthesis

N Hoffmann - Chemical Reviews, 2008 - ACS Publications
Since the beginning of scientific chemistry, chemists have been interested in light as an
energy source to induce chemical reactions. 1 Absorbing light, molecules reach an …

Asymmetric multicomponent reactions (AMCRs): the new frontier

DJ Ramón, M Yus - Angewandte Chemie International Edition, 2005 - Wiley Online Library
Asymmetric multicomponent reactions involve the preparation of chiral compounds by the
reaction of three or more reagents added simultaneously. This kind of addition and reaction …