Soil microorganisms shape global element cycles in life and death. Living soil
microorganisms are a major engine of terrestrial biogeochemistry, driving the turnover of soil …

Biogeography is the study of species distribution and diversity within an ecosystem and is at
the core of how we understand ecosystem dynamics and interactions at the macroscale. In …

We integrated ubiquity, mass and lifespan of all major cell types to achieve a comprehensive
quantitative description of cellular turnover. We found a total cellular mass turnover of 80±20 …

Background Viruses are central to microbial community structure in all environments. The
ability to generate large metagenomic assemblies of mixed microbial and viral sequences …

The genome sequences of many species of the human gut microbiome remain unknown,
largely owing to challenges in cultivating microorganisms under laboratory conditions. Here …

Colon mucus segregates the intestinal microbiota from host tissues, but how it organizes to
function throughout the colon is unclear. In mice, we found that colon mucus consists of two …

The human gut microbiome represents a complex ecosystem contributing essential
functions to its host. Recent large-scale metagenomic studies have provided insights into its …

Bacteriophages typically have small genomes and depend on their bacterial hosts for
replication. Here we sequenced DNA from diverse ecosystems and found hundreds of …

Plant microbiome research highlights the importance of indigenous microbial communities
for host phenotypes such as growth and health. It aims to discover the molecular basis by …

Abstract Characterization of microbiomes has been enabled by high-throughput
metagenomic sequencing. However, existing methods are not designed to combine reads …