Subpopulations of projection neurons in the olfactory bulb

F Imamura, A Ito, BJ LaFever - Frontiers in Neural Circuits, 2020 - frontiersin.org
Generation of neuronal diversity is a biological strategy widely used in the brain to process
complex information. The olfactory bulb is the first relay station of olfactory information in the …

A potential biomarker of preclinical Alzheimer's disease: The olfactory dysfunction and its pathogenesis-based neural circuitry impairments

Y Yan, A Aierken, C Wang, D Song, J Ni, Z Wang… - Neuroscience & …, 2022 - Elsevier
The olfactory dysfunction can signal and act as a potential biomarker of preclinical AD.
However, the precise regulatory mechanism of olfactory function on the neural pathogenesis …

Long-range functional loops in the mouse olfactory system and their roles in computing odor identity

H Chae, A Banerjee, M Dussauze, DF Albeanu - Neuron, 2022 - cell.com
Elucidating the neural circuits supporting odor identification remains an open challenge.
Here, we analyze the contribution of the two output cell types of the mouse olfactory bulb …

Balancing the robustness and efficiency of odor representations during learning

MW Chu, WL Li, T Komiyama - Neuron, 2016 - cell.com
For reliable stimulus identification, sensory codes have to be robust by including
redundancy to combat noise, but redundancy sacrifices coding efficiency. To address how …

Partial depletion of dopaminergic neurons in the substantia nigra impairs olfaction and alters neural activity in the olfactory bulb

W Zhang, C Sun, Y Shao, Z Zhou, Y Hou, A Li - Scientific Reports, 2019 - nature.com
Olfactory dysfunction is a major non-motor symptom that appears during the early stages of
Parkinson's Disease (PD), a neurodegenerative disorder characterized by loss of …

Task-demand-dependent neural representation of odor information in the olfactory bulb and posterior piriform cortex

D Wang, P Liu, X Mao, Z Zhou, T Cao, J Xu… - Journal of …, 2019 - Soc Neuroscience
In awake rodents, the neural representation of olfactory information in the olfactory bulb is
largely dependent on brain state and behavioral context. Learning-modified neural plasticity …

Learning improves decoding of odor identity with phase-referenced oscillations in the olfactory bulb

J Losacco, D Ramirez-Gordillo, J Gilmer, D Restrepo - elife, 2020 - elifesciences.org
Local field potential oscillations reflect temporally coordinated neuronal ensembles—
coupling distant brain regions, gating processing windows, and providing a reference for …

Leptin modulates olfactory discrimination and neural activity in the olfactory bulb

C Sun, K Tang, J Wu, H Xu, W Zhang, T Cao… - Acta …, 2019 - Wiley Online Library
Aim Leptin is an important peptide hormone that regulates food intake and plays a crucial
role in modulating olfactory function. Although a few previous studies have investigated the …

A stable, distributed code for cue value in mouse cortex during reward learning

DJ Ottenheimer, MM Hjort, AJ Bowen, NA Steinmetz… - elife, 2023 - elifesciences.org
The ability to associate reward-predicting stimuli with adaptive behavior is frequently
attributed to the prefrontal cortex, but the stimulus-specificity, spatial distribution, and stability …

Mild myelin disruption elicits early alteration in behavior and proliferation in the subventricular zone

EA Gould, N Busquet, D Shepherd, RM Dietz… - Elife, 2018 - elifesciences.org
Myelin, the insulating sheath around axons, supports axon function. An important question is
the impact of mild myelin disruption. In the absence of the myelin protein proteolipid protein …