T7 RNA polymerase
R Sousa, S Mukherjee, M Kivie - Progress in nucleic acid …, 2003 - books.google.com
Bacteriophage T7 RNA polymerase (RNAP) is the best characterized member of a
widespread family of RNAPs that includes most bacteriophageencoded RNAPs as well as …
widespread family of RNAPs that includes most bacteriophageencoded RNAPs as well as …
A system for the continuous directed evolution of biomolecules
Laboratory evolution has generated many biomolecules with desired properties, but a single
round of mutation, gene expression, screening or selection, and replication typically requires …
round of mutation, gene expression, screening or selection, and replication typically requires …
Engineered nucleic acids encoding a modified erythropoietin and their expression
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Terminally modified RNA
T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
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Engineered nucleic acids and methods of use thereof
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C (= O) C (NC (= O)
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
Modified polynucleotides for the production of biologics and proteins associated with human disease
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
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Modified polynucleotides for the production of secreted proteins
T Chakraborty, A De Fougerolles - US Patent 9,192,651, 2015 - Google Patents
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Engineered nucleic acids and methods of use thereof
S Bancel, JP Schrum, A Aristarkhov - US Patent 9,464,124, 2016 - Google Patents
A61K48/0075—Medicinal preparations containing genetic material which is inserted into
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …
In vivo production of proteins
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
T Chakraborty, A De Fougerolles - US Patent 9,303,079, 2016 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …