A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …

The nature of nervous system function and development is inherently global, since all
components eventually influence one another. Networks communicate through dense …

Understanding the neurobiological underpinnings of emotion relies on objective readouts of
the emotional state of an individual, which remains a major challenge especially in animal …

The posterior parietal cortex (PPC) has an important role in many cognitive behaviours;
however, the neural circuit dynamics underlying PPC function are not well understood. Here …

Linking neural microcircuit function to emergent properties of the mammalian brain requires
fine-scale manipulation and measurement of neural activity during behavior, where each …

Comprehensive measurement of neural activity remains challenging due to the large
numbers of neurons in each brain area. We used volumetric two-photon imaging in mice …

In the absence of salient sensory cues to guide behavior, animals must still execute
sequences of motor actions in order to forage and explore. How such successive motor …

The prefrontal cortex (PFC) plays a key role in controlling goal-directed behavior. Although a
variety of task-related signals have been observed in the PFC, whether they are differentially …

Establishing the hippocampal cellular ensemble that represents an animal's environment
involves the emergence and disappearance of place fields in specific CA1 pyramidal …

Most behaviors, even simple innate reflexes, are mediated by circuits of neurons spanning
areas throughout the brain. However, in most cases, the distribution and dynamics of firing …