The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders
ETC Lippard, CB Nemeroff - American journal of psychiatry, 2023 - psychiatryonline.org
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …
stage of development can have long-lasting consequences. It is associated with a marked …
Childhood adversity and borderline personality disorder: a meta‐analysis
C Porter, J Palmier‐Claus, A Branitsky… - Acta Psychiatrica …, 2020 - Wiley Online Library
Objective The aim of this meta‐analysis was to better understand the magnitude and
consistency of the association between childhood adversity and borderline personality …
consistency of the association between childhood adversity and borderline personality …
The effects of childhood maltreatment on brain structure, function and connectivity
MH Teicher, JA Samson, CM Anderson… - Nature reviews …, 2016 - nature.com
Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …
illness and substance abuse. Although the association between maltreatment and …
A systematic review of childhood maltreatment and DNA methylation: candidate gene and epigenome-wide approaches
Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …
health problems across the lifespan. Increasing evidence supports the hypothesis that …
Borderline personality disorder and substance use disorders: an updated review
TJ Trull, LK Freeman, TJ Vebares, AM Choate… - … personality disorder and …, 2018 - Springer
For decades, clinicians and researchers have recognized that borderline personality
disorder (BPD) and substance use disorders (SUDs) are often diagnosed within the same …
disorder (BPD) and substance use disorders (SUDs) are often diagnosed within the same …
[HTML][HTML] Childhood maltreatment and DNA methylation: A systematic review
DNA methylation (DNAm)–an epigenetic process that regulates gene expression–may
represent a mechanism for the biological embedding of early traumatic experiences …
represent a mechanism for the biological embedding of early traumatic experiences …
Epigenetics in depression and gut-brain axis: A molecular crosstalk
N Begum, A Mandhare, KP Tryphena… - Frontiers in Aging …, 2022 - frontiersin.org
Gut-brain axis is a dynamic, complex, and bidirectional communication network between the
gut and brain. Changes in the microbiota-gut-brain axis are responsible for developing …
gut and brain. Changes in the microbiota-gut-brain axis are responsible for developing …
Borderline personality disorder and childhood trauma: exploring the affected biological systems and mechanisms
N Cattane, R Rossi, M Lanfredi, A Cattaneo - BMC psychiatry, 2017 - Springer
Background According to several studies, the onset of the Borderline Personality Disorder
(BPD) depends on the combination between genetic and environmental factors (GxE), in …
(BPD) depends on the combination between genetic and environmental factors (GxE), in …
Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation
S Brummelte, E Mc Glanaghy, A Bonnin, TF Oberlander - Neuroscience, 2017 - Elsevier
Abstract The neurotransmitter serotonin (5-HT) plays a central role in brain development,
regulation of mood, stress reactivity and risk of psychiatric disorders, and thus alterations in …
regulation of mood, stress reactivity and risk of psychiatric disorders, and thus alterations in …
Biomarkers of suicide attempt behavior: towards a biological model of risk
K Sudol, JJ Mann - Current psychiatry reports, 2017 - Springer
Abstract Purpose of Review The rising suicide rate in the USA will not be reversed without
improved risk assessment and prevention practices. To date, the best method for clinicians …
improved risk assessment and prevention practices. To date, the best method for clinicians …