Near-infrared luminescence high-contrast in vivo biomedical imaging

Y Chen, S Wang, F Zhang - Nature Reviews Bioengineering, 2023 - nature.com
Luminescence imaging in biomedical research has allowed new insights into the
architecture of pathological tissues, signalling networks and cell interactions, and is now …

In vivo fluorescence imaging: success in preclinical imaging paves the way for clinical applications

A Refaat, ML Yap, G Pietersz, APG Walsh… - Journal of …, 2022 - Springer
Advances in diagnostic imaging have provided unprecedented opportunities to detect
diseases at early stages and with high reliability. Diagnostic imaging is also crucial to …

Rational design of a double-locked photoacoustic probe for precise in vivo imaging of cathepsin B in atherosclerotic plaques

Y Ma, J Shang, L Liu, M Li, X Xu, H Cao… - Journal of the …, 2023 - ACS Publications
Atherosclerotic plaque rupture is a significant cause of acute cardiovascular events such as
heart attack and stroke, triggered by the decomposition of fiber caps induced by cysteine …

Repurposing cyanine NIR‐I dyes accelerates clinical translation of near‐infrared‐II (NIR‐II) bioimaging

S Zhu, Z Hu, R Tian, BC Yung, Q Yang… - Advanced …, 2018 - Wiley Online Library
The significantly reduced tissue autofluorescence and scattering in the NIR‐II region (1000–
1700 nm) opens many exciting avenues for detailed investigation of biological processes in …

Immune cell profiling in atherosclerosis: role in research and precision medicine

DM Fernandez, C Giannarelli - Nature Reviews Cardiology, 2022 - nature.com
Inflammation is intimately involved at all stages of atherosclerosis and remains a substantial
residual cardiovascular risk factor in optimally treated patients. The proof of concept that …

[HTML][HTML] Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles

W Tong, H Hui, W Shang, Y Zhang, F Tian, Q Ma… - Theranostics, 2021 - ncbi.nlm.nih.gov
Inflammation is a pivotal driver of atherosclerotic plaque progression and rupture and is a
target for identifying vulnerable plaques. However, challenges arise with the current in vivo …

Highly bright AIE nanoparticles by regulating the substituent of rhodanine for precise early detection of atherosclerosis and drug screening

K Wang, H Gao, Y Zhang, H Yan, J Si, X Mi… - Advanced …, 2022 - Wiley Online Library
Fluorescent probes capable of precise detection of atherosclerosis (AS) at an early stage
and fast assessment of anti‐AS drugs in animal level are particularly valuable. Herein, a …

[HTML][HTML] Intracoronary optical coherence tomography: state of the art and future directions: State of the art in OCT

Z Ali, KK Galougahi, GS Mintz, A Maehara… - …, 2021 - ncbi.nlm.nih.gov
Optical coherence tomography (OCT) has been increasingly utilised to guide percutaneous
coronary intervention (PCI). Despite the diagnostic utility of OCT, facilitated by its high …

Myocardial infarction—From atherosclerosis to thrombosis: Uncovering new diagnostic and therapeutic approaches

J Palasubramaniam, X Wang… - … , thrombosis, and vascular …, 2019 - Am Heart Assoc
One of the earliest and best-recognized elements of atherosclerosis is its close relationship
with circulating LDL (low-density lipoprotein). There is convincing evidence that LDL …

Sensitive magnetic particle imaging of haemoglobin degradation for the detection and monitoring of intraplaque haemorrhage in atherosclerosis

W Tong, Y Zhang, H Hui, X Feng, B Ning, T Yu… - …, 2023 - thelancet.com
Background Intraplaque haemorrhage (IPH) drives atherosclerosis progression and is a key
imaging biomarker of unstable plaques. Non-invasive and sensitive monitoring of IPH is …