Abstract RNA polymerase II (RNA Pol II) speed or elongation rate, ie, the number of
nucleotides synthesized per unit of time, is a major determinant of transcriptome …

Plants have an extraordinary diversity of transcription machineries, including five nuclear
DNA-dependent RNA polymerases. Four of these enzymes are dedicated to the production …

Physiological homeostasis becomes compromised during ageing, as a result of impairment
of cellular processes, including transcription and RNA splicing,,–. However, the molecular …

In most organisms, the maturation of nascent RNAs is coupled to transcription. Unlike in
animals, the RNA polymerase II (RNAPII) transcribes microRNA genes (MIRNA s) as long …

The activities of RNA polymerases shape the epigenetic landscape of genomes with
profound consequences for genome integrity and gene expression. A fundamental event …

Transcriptional elongation by RNA polymerase II (RNAPII) through chromatin is a dynamic
and highly regulated step of eukaryotic gene expression. A combination of transcript …

To be properly expressed, genes need to be accompanied by a terminator, a region
downstream of the coding sequence that contains the information necessary for the …

The precise spatiotemporal gene expression is orchestrated by enhancers that lack general
sequence features and thus are difficult to be computationally identified. By nascent RNA …

Background Alternative splicing (AS), a posttranscriptional process, contributes to the
complexity of transcripts from a limited number of genes in a genome, and AS is considered …

Alternative splicing (AS) is a major gene regulatory mechanism in plants. Recent evidence
supports co‐transcriptional splicing in plants, hence the chromatin state can impact AS …