Discerning the prospects of miRNAs as a multi-target therapeutic and diagnostic for alzheimer's disease

D Bhatnagar, S Ladhe, D Kumar - Molecular Neurobiology, 2023 - Springer
Although over the last few decades, numerous attempts have been made to halt Alzheimer's
disease (AD) progression and mitigate its symptoms, only a few have been proven …

Extracellular vesicles (exosomes and ectosomes) play key roles in the pathology of brain diseases

J Meldolesi - Molecular biomedicine, 2021 - Springer
Last century, neurons and glial cells were mostly believed to play distinct functions, relevant
for the brain. Progressively, however, it became clear that neurons, astrocytes and microglia …

Aggregation induced emission based active conjugated imidazole luminogens for visualization of latent fingerprints and multiple anticounterfeiting applications

MK Ravindra, GP Darshan, DR Lavanya… - Scientific reports, 2021 - nature.com
Aggregation-induced emission based organic heterocyclic luminogens bearing conjugated
electronic structures showed much attention due to its excellent fluorescence in aggregation …

Variability of multi-omics profiles in a population-based child cohort

M Gallego-Paüls, C Hernández-Ferrer, M Bustamante… - BMC medicine, 2021 - Springer
Background Multiple omics technologies are increasingly applied to detect early, subtle
molecular responses to environmental stressors for future disease risk prevention. However …

Urinary microRNAs and their significance in prostate cancer diagnosis: a 5-year update

J Juracek, M Madrzyk, M Stanik, O Slaby - Cancers, 2022 - mdpi.com
Simple Summary Current diagnostics of prostate cancer often show unsatisfactory results,
leading to delayed detection or overtreatment. Urinary microRNAs are a class of promising …

Role and Dysregulation of miRNA in Patients with Parkinson's Disease

M Salemi, G Marchese, G Lanza, FII Cosentino… - International Journal of …, 2022 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative synucleinopathy that has a not yet fully
understood molecular pathomechanism behind it. The role of risk genes regulated by small …

Evaluation of serum miR‐191‐5p, miR‐24‐3p, miR‐128‐3p, and miR‐376c‐3 in multiple sclerosis patients

J Vistbakka, ML Sumelahti, T Lehtimäki… - Acta Neurologica …, 2018 - Wiley Online Library
Background Biomarkers that could be used in early diagnosis of multiple sclerosis (MS),
segregation of disease subtypes, and discrimination of the aggressive disease course from …

microRNA heterogeneity, innate-immune defense and the efficacy of SARS-CoV-2 infection—A commentary

WJ Lukiw - Non-coding RNA, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a member of the genus
Betacoronavirus in the family Coronaviridae, possesses an unusually large single-stranded …

Brain-enriched MicroRNA-184 is downregulated in older adults with major depressive disorder: A translational study

AP Mendes-Silva, PT Fujimura… - Journal of psychiatric …, 2019 - Elsevier
Abstract Changes in microRNAs (miRNAs) expression have been described in major
depressive disorder in young and middle-aged adults. However, no study has evaluated …

Extracellular vesicles and their associated mirnas as potential biomarkers in intracranial aneurysm

Y Li, J Wen, D Liang, H Sun - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Intracranial aneurysms (IA) are abnormal expansions of the intracranial arteries. Once it
ruptures, the mortality and disability rate are high. The cost of imaging examinations is high …