Most patients survive acute myocardial infarction (MI). Yet this encouraging development
has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend …

Tissue inhibitor of metalloproteinase 3 (TIMP3) is unique among the four TIMPs due to its
extracellular matrix (ECM)-binding property and broad range of inhibitory substrates that …

Myocardial infarction (MI) is the leading cause of morbidity and mortality worldwide. Despite
extensive efforts to provide early diagnosis and adequate treatment regimens, detection of …

Nuclear imaging techniques can detect and quantify pathophysiological processes
underlying heart failure, complementing evaluation of cardiac structure and function with …

The extracellular matrix (ECM) plays important roles in maintaining physiological structure
and functions of various tissues and organs. Cardiac fibrosis is the excess deposition of …

The development of new radiotracers for PET and SPECT is central to addressing unmet
diagnostic needs related to systemwide trends toward molecular characterization and …

Following myocardial infarction (MI), maladaptive upregulation of matrix metalloproteinase
(MMP) alters extracellular matrix leading to cardiac remodeling. Intramyocardial hydrogel …

Molecular imaging can detect and quantify pathophysiological processes underlying heart
failure, complementing evaluation of cardiac structure and function with other imaging …

Myocardial infarction (MI) is one of the leading causes of morbidity and mortality worldwide.
The immune response plays a central role in post-MI cardiac repair. A growing body of …

Background Left ventricular (LV) remodeling following a myocardial infarction (MI) is
associated with new-onset atrial fibrillation (AF). LV remodeling post-MI is characterized by …