As the Global Polio Eradication Initiative (GPEI) strategizes towards the final steps of
eradication, routine immunization schedules evolve, and high-quality vaccination …

A sharp rise in circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreaks in the years
following the cessation of routine use of poliovirus type 2-containing oral polio vaccine and …

With the COVID-19 pandemic abating, the only remaining Public Health Emergency of
International Concern is polio [1]. Remarkable progress has been made in reducing the …

Delays in achieving polio eradication have led to ongoing risks of poliovirus importations
that may cause outbreaks in polio-free countries. Because of the low, but non-zero risk of …

Continued investment in the development and application of mathematical models of
poliovirus transmission, economics, and risks leads to their use in support of polio endgame …

Inactivated poliovirus vaccine (IPV), available since 1955, became the first vaccine to be
used to protect against poliomyelitis. While the immunogenicity of IPV to prevent paralytic …

Abstract Background Although polioviruses (PVs) replicate in lymphoid tissue of both the
pharynx and ileum, research on polio vaccine-induced mucosal immunity has predominantly …

Poliomyelitis is a potentially disabling, life-threatening and outbreak-prone disease caused
by infection by 1 of 3 different serotypes of poliovirus (type-1, type-2, or type-3). Polioviruses …