Clonal hematopoiesis of indeterminate potential (CHIP) has emerged as a previously
unrecognized, potent, age-related, and common risk factor for atherosclerosis. Somatic …

Clonal hematopoiesis (CH) arises when a substantial proportion of mature blood cells is
derived from a single hematopoietic stem cell lineage. Using whole-genome sequencing of …

Clonal hematopoiesis of indeterminate potential (CHIP) is a common bone marrow
abnormality induced by age‐related DNA mutations, which give rise to proinflammatory …

Background Clonal hematopoiesis of indeterminate potential (CHIP)—the age-related clonal
expansion of blood stem cells with leukemia-associated mutations—is a novel …

Clonal hematopoiesis, a condition in which acquired somatic mutations in hematopoietic
stem cells lead to the outgrowth of a mutant hematopoietic clone, is associated with a higher …

Abstract Aims Interleukin-6 (IL-6) and interleukin-18 (IL-18), important cytokines implicated
in atherosclerosis and inflammaging, were assessed for associations with global …

Clonal hematopoiesis of indeterminate potential (CHIP) has been associated with an
increased risk of cardiovascular (CV) disease in the general population. Currently, it is …

Age is a predominant risk factor for acute kidney injury (AKI), yet the biological mechanisms
underlying this risk are largely unknown. Clonal hematopoiesis of indeterminate potential …

Abstract Background and Aims Clonal haematopoiesis of indeterminate potential (CHIP), the
age-related expansion of blood cells with preleukemic mutations, is associated with …

Clonal hematopoiesis (CH) increases the risk of atherosclerotic cardiovascular disease
possibly due to increased plaque inflammation. Human studies suggest that limitation of …