[HTML][HTML] Current advances in synchrotron radiation instrumentation for MX experiments

RL Owen, J Juanhuix, M Fuchs - Archives of Biochemistry and Biophysics, 2016 - Elsevier
Following pioneering work 40 years ago, synchrotron beamlines dedicated to
macromolecular crystallography (MX) have improved in almost every aspect as …

Automated technologies and novel techniques to accelerate protein crystallography for structural genomics

BA Manjasetty, AP Turnbull, S Panjikar, K Büssow… - …, 2008 - Wiley Online Library
The sequence infrastructure that has arisen through large‐scale genomic projects dedicated
to protein analysis, has provided a wealth of information and brought together scientists and …

Microfluidic chips for the crystallization of biomacromolecules by counter-diffusion and on-chip crystal X-ray analysis

K Dhouib, CK Malek, W Pfleging, B Gauthier-Manuel… - Lab on a Chip, 2009 - pubs.rsc.org
Microfluidic devices were designed to perform on micromoles of biological macromolecules
and viruses the search and the optimization of crystallization conditions by counter-diffusion …

[HTML][HTML] In crystallo optical spectroscopy (icOS) as a complementary tool on the macromolecular crystallography beamlines of the ESRF

D von Stetten, T Giraud, P Carpentier… - … Section D: Biological …, 2015 - scripts.iucr.org
The analysis of structural data obtained by X-ray crystallography benefits from information
obtained from complementary techniques, especially as applied to the crystals themselves …

[PDF][PDF] DA+ data acquisition and analysis software at the Swiss Light Source macromolecular crystallography beamlines

JA Wojdyla, JW Kaminski, E Panepucci… - Journal of …, 2018 - journals.iucr.org
Data acquisition software is an essential component of modern macromolecular
crystallography (MX) beamlines, enabling efficient use of beam time at synchrotron facilities …

SLS Crystallization Platform at Beamline X06DAA Fully Automated Pipeline Enabling in Situ X-ray Diffraction Screening

R Bingel-Erlenmeyer, V Olieric… - Crystal growth & …, 2011 - ACS Publications
The third beamline for macromolecular crystallography at the superbend magnet X06DA of
the Swiss Light Source (SLS) was designed for maximum efficiency and a high degree of …

[PDF][PDF] Exploiting fast detectors to enter a new dimension in room-temperature crystallography

RL Owen, N Paterson, D Axford, J Aishima… - … Section D: Biological …, 2014 - journals.iucr.org
A departure from a linear or an exponential intensity decay in the diffracting power of protein
crystals as a function of absorbed dose is reported. The observation of a lag phase raises …

Trace fluorescent labeling for high-throughput crystallography

E Forsythe, A Achari, ML Pusey - Acta Crystallographica Section D …, 2006 - journals.iucr.org
Covalent labeling of macromolecules with trace levels (< 1%) of a fluorescent dye is
proposed as a means to facilitate finding or detecting crystals in crystallization drops. To test …

[HTML][HTML] Automation of macromolecular crystallography beamlines

S Arzt, A Beteva, F Cipriani, S Delageniere… - Progress in biophysics …, 2005 - Elsevier
The production of three-dimensional crystallographic structural information of
macromolecules can now be thought of as a pipeline which is being streamlined at every …

[HTML][HTML] A capillary-based microfluidic device enables primary high-throughput room-temperature crystallographic screening

S Sui, A Mulichak, R Kulathila, J McGee… - Journal of Applied …, 2021 - scripts.iucr.org
A novel capillary-based microfluidic strategy to accelerate the process of small-molecule-
compound screening by room-temperature X-ray crystallography using protein crystals is …