A review on advances of treatment modalities for Alzheimer's disease

ES Thoe, A Fauzi, YQ Tang, S Chamyuang, AYY Chia - Life sciences, 2021 - Elsevier
Alzheimer's disease (AD) is a multifactorial neurodegenerative disease which is mainly
characterized by progressive impairment in cognition, emotion, language and memory in …

Alzheimer's retinopathy: seeing disease in the eyes

N Mirzaei, H Shi, M Oviatt, J Doustar… - Frontiers in …, 2020 - frontiersin.org
The neurosensory retina emerges as a prominent site of Alzheimer's disease (AD)
pathology. As a CNS extension of the brain, the neuro retina is easily accessible for …

Detection of β-amyloid positivity in Alzheimer's Disease Neuroimaging Initiative participants with demographics, cognition, MRI and plasma biomarkers

D Tosun, D Veitch, P Aisen, CR Jack Jr… - Brain …, 2021 - academic.oup.com
In vivo gold standard for the ante-mortem assessment of brain β-amyloid pathology is
currently β-amyloid positron emission tomography or cerebrospinal fluid measures of β …

Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer's disease

JD Whitesell, AR Buckley, JE Knox… - Journal of …, 2019 - Wiley Online Library
A variety of Alzheimer's disease (AD) mouse models overexpress mutant forms of human
amyloid precursor protein (APP), producing high levels of amyloid β (Aβ) and forming …

Diagnóstico da doença de Alzheimer: recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de …

LP Schilling, MLF Balthazar, M Radanovic… - Dementia & …, 2022 - SciELO Brasil
Este artigo apresenta o consenso realizado pelo Departamento Científico de Neurologia
Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia sobre os critérios …

Advanced overview of biomarkers and techniques for early diagnosis of alzheimer's disease

S Rani, SB Dhar, A Khajuria, D Gupta… - Cellular and Molecular …, 2023 - Springer
The development of early non-invasive diagnosis methods and identification of novel
biomarkers are necessary for managing Alzheimer's disease (AD) and facilitating effective …

Application of 89Zr-DFO*-immuno-PET to assess improved target engagement of a bispecific anti-amyloid-ß monoclonal antibody

N Stergiou, TE Wuensche, M Schreurs, I Mes… - European journal of …, 2023 - Springer
Purpose The recent conditional FDA approval of Aducanumab (Adu) for treating Alzheimer's
disease (AD) and the continued discussions around that decision have increased interest in …

Relevance of plasma biomarkers to pathologies in Alzheimer's disease, Parkinson's disease and frontotemporal dementia

PY Chiu, FC Yang, MJ Chiu, WC Lin, CH Lu… - Scientific Reports, 2022 - nature.com
Amyloid plaques and tau tangles are pathological hallmarks of Alzheimer's disease (AD).
Parkinson's disease (PD) results from the accumulation of α-synuclein. TAR DNA-binding …

Mass spectrometry: A platform for biomarker discovery and validation for Alzheimer's and Parkinson's diseases

EM Cilento, L Jin, T Stewart, M Shi… - Journal of …, 2019 - Wiley Online Library
Accurate, reliable, and objective biomarkers for Alzheimer's disease (AD), Parkinson's
disease (PD), and related age‐associated neurodegenerative disorders are urgently …

Early stage glycosylation biomarkers in Alzheimer's disease

P Regan, PL McClean, T Smyth, M Doherty - Medicines, 2019 - mdpi.com
Alzheimer's disease (AD) is of great cause for concern in our ageing population, which
currently lacks diagnostic tools to permit accurate and timely diagnosis for affected …