Carbazoles represent an important class of heterocycles. These have been reported to
exhibit diverse biological activities such as antimicrobial, antitumor, antiepileptic …

For over half a century, the carbazole skeleton has been the key structural motif of many
biologically active compounds including natural and synthetic products. Carbazoles have …

An enantioselective functionalization of the indole NH group is developed. The reaction
stereoselectivity is controlled by an N-heterocyclic carbene catalyst that adds to an aldehyde …

This article demonstrates recent innovative cascade annulation methods for preparing
functionalized carbazoles and their related polyaromatic heterocyclic compounds enabled …

This study reports the synthesis and characterization of two new mono-and di-substituted
phthalonitriles namely 4-((9H-carbazol-3-yl) oxy)-5-chlorophthalonitrile and 4, 5-bis ((9H …

The Ru (II)-catalyzed tunable [5+ 1]/[5+ 2] annulation of N-benzo [d] imidazole indolines with
propargyl carbonates has been realized for the divergent synthesis of ring-fused …

ABC-transporters play a vital role in drugs bioavailability. They prevent intracellular
accumulation of toxic compounds, rendering them a major defense mechanism against …

A copper-catalyzed, directed ortho C–H diarylamination of indoles, indolines, anilines, and
N-aryl-7-azaindoles has been established. Only copper salt as the catalyst and oxygen as …

A new series of 2-amino-4-phenyl-6-hydroxy-7-alkyl-pyranobenzoquinones was
synthesized as ATP-competitive CK2 inhibitors. They were readily synthesized through a …

Abstract Carbonic anhydrases (CAs, EC4. 2.1. 1) are metalloenzymes that catalyse
reversible hydration reaction of carbon dioxide to bicarbonate and protons. In recent years …