Transmembrane proteins of the tetraspanin superfamily are implicated in a broad spectrum
of cellular processes in many biological systems in both health and disease. Tetraspanins …

Transmembrane protein tetraspanins either promote or suppress tumor invasion and
metastasis. Their effects on tumor progression depend on the multimolecular …

Purpose Oral cancer (OC) patients are at high risk to develop recurrent disease or
secondary primary cancers with no available biomarkers to detect these events until a …

Retrograde flow of menstrual blood cells during menstruation is considered as the dominant
theory for the development of endometriosis. Moreover, current evidence suggests that …

Ultracentrifugation remains the gold standard for isolation of small extracellular vesicles
(sEV), particularly for cancer applications. The objective of this study was to determine if a …

Tetraspanin 8 (TSPAN8) is a member of the tetraspanin superfamily that forms TSPAN8-
mediated protein complexes by interacting with themselves and other various cellular …

Background: Bone is a preferred target for circulating metastatic breast cancer cells. We
found that the CD9 protein was up-regulated in the B02 osteotropic cell line, derived from …

Background CD9 is implicated in cancer progression and metastasis by its role in
suppressing cancer cell proliferation and survival. However, the prognostic and …

Simple Summary Considering the high incidence of colorectal cancer in adults, as well as
the need for identifying novel therapies, we hereby explore the role of tetraspanins in the …

The diagnosis of parathyroid carcinoma can be challenging, and adjuvant therapies such as
radiotherapy and chemotherapy are not particularly beneficial in the management of this …