The signaling duo CXCL12 and CXCR4: chemokine fuel for breast cancer tumorigenesis

KA Zielińska, VL Katanaev - Cancers, 2020 - mdpi.com
Simple Summary Breast cancer remains the most common malignancy in women. In this
review, we explore the role of the CXCL12/CXCR4 pathway in breast cancer. We show that …

PPARs and tumor microenvironment: the emerging roles of the metabolic master regulators in tumor stromal–epithelial crosstalk and carcinogenesis

HS Cheng, YS Yip, EKY Lim, W Wahli, NS Tan - Cancers, 2021 - mdpi.com
Simple Summary The roles of peroxisome proliferator-activated receptors (PPARs) in
carcinogenesis are increasingly appreciated. With the growing interest in tumor stromal …

Identification of Key Genes and Biological Pathways Associated with Skeletal Muscle Maturation and Hypertrophy in Bos taurus, Ovis aries, and Sus scrofa

F Mohammadinejad, M Mohammadabadi, Z Roudbari… - Animals, 2022 - mdpi.com
Simple Summary One of the traits considered in livestock production is the gain of muscle
mass, which is one of the factors responsible for governing the growth of skeletal muscles …

Peroxisome proliferator‐activated receptor modulation during metabolic diseases and cancers: master and minions

SG Vitale, AS Laganà, A Nigro, VL La Rosa… - PPAR …, 2016 - Wiley Online Library
The prevalence of obesity and metabolic diseases (such as type 2 diabetes mellitus,
dyslipidaemia, and cardiovascular diseases) has increased in the last decade, in both …

Nutraceuticals in the Mediterranean diet: potential avenues for breast cancer treatment

G Augimeri, FI Montalto, C Giordano, I Barone… - Nutrients, 2021 - mdpi.com
The traditional Mediterranean Diet constitutes a food model that refers to the dietary patterns
of the population living in countries bordering the Mediterranean Sea in the early 1960s. A …

The CXCL12 (SDF-1)/CXCR4 chemokine axis: Oncogenic properties, molecular targeting, and synthetic and natural product CXCR4 inhibitors for cancer therapy

Z Yu, CAO Han-Bo, LI Wen-Jun, Z Li - Chinese journal of natural medicines, 2018 - Elsevier
Abstract Chemokine 12 (CXCL12), also known as stromal cell derived factor-1 (SDF-1) and
a member of the CXC chemokine subfamily, is ubiquitously expressed in many tissues and …

Anti-Inflammatory and Antioxidant Effects of Leaves and Sheath from Bamboo (Phyllostacys edulis J. Houz)

R Tundis, G Augimeri, A Vivacqua, R Romeo, V Sicari… - Antioxidants, 2023 - mdpi.com
Bamboo (Phyllostacys edulis J. Houz) has become an emerging forest resource of economic
and ecological significance with health benefits. Since the beneficial effects of the non …

Peroxisome proliferator-activated receptors and the hallmarks of cancer

N Wagner, KD Wagner - Cells, 2022 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) function as nuclear transcription factors
upon the binding of physiological or pharmacological ligands and heterodimerization with …

Lysine metabolism is a novel metabolic tumor suppressor pathway in breast cancer

J Wu, K Kramer, DL Crowe - Oncogene, 2023 - nature.com
Abstract The International Agency for Research on Cancer determined that obesity is the
primary preventable cause of breast cancer. The nuclear receptor peroxisome proliferator …

Antioxidant and anti-inflammatory effects of extracts from pulsed electric field-treated artichoke by-products in lipopolysaccharide-stimulated human THP-1 …

S Carpentieri, G Augimeri, J Ceramella, A Vivacqua… - Foods, 2022 - mdpi.com
In this study, pulsed electric field (PEF—3 kV/cm; 5 kJ/kg) pretreatment was used to intensify
the extractability of valuable intracellular compounds from artichoke by-products during a …