Photodynamic therapy—current limitations and novel approaches

G Gunaydin, ME Gedik, S Ayan - Frontiers in Chemistry, 2021 - frontiersin.org
Photodynamic therapy (PDT) mostly relies on the generation of singlet oxygen, via the
excitation of a photosensitizer, so that target tumor cells can be destroyed. PDT can be …

Oncologic photodynamic therapy: basic principles, current clinical status and future directions

D Van Straten, V Mashayekhi, HS De Bruijn, S Oliveira… - Cancers, 2017 - mdpi.com
Photodynamic therapy (PDT) is a clinically approved cancer therapy, based on a
photochemical reaction between a light activatable molecule or photosensitizer, light, and …

[HTML][HTML] Photodynamic therapy combined with immunotherapy: Recent advances and future research directions

M Warszyńska, P Repetowski, JM Dąbrowski - Coordination Chemistry …, 2023 - Elsevier
Innovative anticancer therapies based on the activation of the immune system offer promise
in the battle against cancers resistant to traditional treatments. Examples of such therapeutic …

Photodynamic therapy mediated by nontoxic core–shell nanoparticles synergizes with immune checkpoint blockade to elicit antitumor immunity and antimetastatic …

X Duan, C Chan, N Guo, W Han… - Journal of the …, 2016 - ACS Publications
An effective, nontoxic, tumor-specific immunotherapy is the ultimate goal in the battle against
cancer, especially the metastatic disease. Checkpoint blockade-based immunotherapies …

Photodynamic and photothermal co-driven CO-enhanced multi-mode synergistic antibacterial nanoplatform to effectively fight against biofilm infections

X Cai, J Tian, J Zhu, J Chen, L Li, C Yang… - Chemical Engineering …, 2021 - Elsevier
Photothermal therapy (PTT) and photodynamic therapy (PDT) have garnered much attention
for effectively treating biofilm infections. However, even highly efficient PTT reagents and …

Neutrophil‐based drug delivery systems

D Chu, X Dong, X Shi, C Zhang, Z Wang - Advanced materials, 2018 - Wiley Online Library
White blood cells (WBCs) are a major component of immunity in response to pathogen
invasion. Neutrophils are the most abundant WBCs in humans, playing a central role in …

[HTML][HTML] Beyond the barriers of light penetration: strategies, perspectives and possibilities for photodynamic therapy

S Mallidi, S Anbil, AL Bulin, G Obaid, M Ichikawa… - Theranostics, 2016 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) is a photochemistry based treatment modality that involves the
generation of cytotoxic species through the interactions of a photosensitizer molecule with …

Photodynamic therapy (PDT) of cancer: from local to systemic treatment

JM Dąbrowski, LG Arnaut - Photochemical & Photobiological Sciences, 2015 - pubs.rsc.org
Photodynamic therapy (PDT) requires a medical device, a photosensitizing drug and
adequate use of both to trigger biological mechanisms that can rapidly destroy the primary …

Photodynamic therapy of cancer: an update

P Agostinis, K Berg, KA Cengel… - CA: a cancer journal …, 2011 - Wiley Online Library
Photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic
procedure that can exert a selective cytotoxic activity toward malignant cells. The procedure …

[HTML][HTML] Photodynamic therapy (PDT): PDT mechanisms

RR Allison, K Moghissi - Clinical endoscopy, 2013 - synapse.koreamed.org
Photodynamic therapy (PDT) is a light based therapy used to ablate tumors. As practiced in
oncology a photosensitizing agent is applied and then activated by a specific wavelength …