Preparation and application of pH-responsive drug delivery systems

H Ding, P Tan, S Fu, X Tian, H Zhang, X Ma… - Journal of Controlled …, 2022 - Elsevier
Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …

Extraction, structure, pharmacological activities and drug carrier applications of Angelica sinensis polysaccharide

J Nai, C Zhang, H Shao, B Li, H Li, L Gao, M Dai… - International journal of …, 2021 - Elsevier
Angelica sinensis polysaccharide (ASP) is one of the main active components of Angelica
sinensis (AS) that is widely used in traditional Chinese medicine. ASP is water-soluble …

Metformin modified chitosan as a multi-functional adjuvant to enhance cisplatin-based tumor chemotherapy efficacy

Z Zhou, Y Liu, X Jiang, C Zheng, W Luo, X Xiang… - International Journal of …, 2023 - Elsevier
Recently, it was newly revealed that the DNA damage induced by cis‑platinum (Cis-Pt)
mediated chemotherapy was significantly impaired by the highly expressed programmed …

Smart materials for drug delivery and cancer therapy

Y Yang, W Zeng, P Huang, X Zeng, L Mei - View, 2021 - Wiley Online Library
Until now, enormous smart materials have been engineered with endogenous stimulators
such as pH, reactive oxygen species, glutathione, hypoxia and enzyme, or exogenous …

Modifications of polysaccharide-based biomaterials under structure-property relationship for biomedical applications

M Luo, X Zhang, J Wu, J Zhao - Carbohydrate Polymers, 2021 - Elsevier
Polysaccharides are well accepted biomaterials that have attracted considerable attention.
Compared with other materials under research, polysaccharides show unique advantages …

Polysaccharide-based tumor microenvironment-responsive drug delivery systems for cancer therapy

Q Wu, Y Hu, B Yu, H Hu, FJ Xu - Journal of Controlled Release, 2023 - Elsevier
The biochemical indicators of tumor microenvironment (TME) that are different from normal
tissues provide the possibility for constructing intelligent drug delivery systems (DDSs) …

Subcellular visualization: organelle-specific targeted drug delivery and discovery

X Shao, C Meng, W Song, T Zhang, Q Chen - Advanced Drug Delivery …, 2023 - Elsevier
Organelles perform critical biological functions due to their distinct molecular composition
and internal environment. Disorders in organelles or their interacting networks have been …

Layer-by-layer oral-deliverable nanoparticles targeted microfold cells to promote lutein absorption in alleviating dry eye disease

R Liu, S Fei, X Zhang, Z Hua, M Tan - Chemical Engineering Journal, 2024 - Elsevier
Bioactive compound intervention of dry eye disease has been considered as a promising
approach due to the lower adverse reactions. In this study, layer-by-layer oral-deliverable …

pH and amylase dual stimuli-responsive electrospinning membrane for smart releasing thymol to control melon Rhizopus stolonifer

H Du, X Sun, X Bian, W Zhang, J Xie, Z Zhu… - Chemical Engineering …, 2023 - Elsevier
Antimicrobial active packaging was limited by the inability to release the antimicrobial
agents at the required location, required time, and required quantity. Hence, it is necessary …

Recent advances in plant polysaccharide-mediated nano drug delivery systems

Y Zheng, Q Xie, H Wang, Y Hu, B Ren, X Li - International Journal of …, 2020 - Elsevier
Plant polysaccharides with multiple biological activities and health benefit effects are usually
considered as natural active macromolecules in food and medicine dual purposes plant …