In 1960, immunoassays of insulin first demonstrated significant quantities of circulating
hormone in non-insulin-dependent (type II) diabetes and for 30 yr have fostered debate as to …

ISLETβ-cells play a central role in the regulation of most cells in the body through secretion
of insulin. These cells are now known to secrete a second hormone-like protein, amylin, also …

The aim of this paper is to review the information on type 1 and type 2 diabetes with
emphasis on its etiology, pathogenesis and pathophysiology via literature review. Diabetes …

Islet amyloid polypeptide (IAPP) and insulin are copackaged and cosecreted by pancreatic
islet β-cells. Non-insulin-dependent (type II) diabetes mellitus (NIDDM) is characterized by …

Human adipose tissue is a contributor to inflammation-and sepsis-induced elevation of
serum procalcitonin (ProCT). Several calcitonin (CT) peptides, including ProCT, CT gene …

Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse biological effects
including potent vasodilator activity. We report here the cloning of a complementary DNA …

Background & aims Gestational diabetes mellitus (GDM) may increase the future health risks
of women and their offspring. The aim of this study was to determine the effect of capsaicin …

Background We recently found that brain tissue from patients with type-2 diabetes (T2D) and
cognitive impairment contains deposits of amylin, an amyloidogenic hormone synthesized …

Islet amyloid polypeptide (IAPP or amylin) is costored and cosecreted with insulin and may
regulate insulin secretion and blood glucose handling. However, the role and importance of …

Fasting plasma islet amyloid polypeptide concentrations and their responses to an oral
glucose load were determined in non-diabetic control subjects and patients with abnormal …