Biology of Borrelia species
AG Barbour, SF Hayes - Microbiological reviews, 1986 - Am Soc Microbiol
Relapsing fever was known to the physicians of ancient Greece and possibly to those of an
earlier civilization in Egypt (92, 180). Extensive epidemics of louse-borne relaps-ing fever …
earlier civilization in Egypt (92, 180). Extensive epidemics of louse-borne relaps-ing fever …
The biological and social phenomenon of Lyme disease
AG Barbour, D Fish - Science, 1993 - science.org
Lyme disease, unknown in the United States two decades ago, is now the most common
arthropod-borne disease in the country and has caused considerable morbidity in several …
arthropod-borne disease in the country and has caused considerable morbidity in several …
An ecological approach to preventing human infection: vaccinating wild mouse reservoirs intervenes in the Lyme disease cycle
JI Tsao, JT Wootton, J Bunikis… - Proceedings of the …, 2004 - National Acad Sciences
Many pathogens, such as the agents of West Nile encephalitis and plague, are maintained
in nature by animal reservoirs and transmitted to humans by arthropod vectors. Efforts to …
in nature by animal reservoirs and transmitted to humans by arthropod vectors. Efforts to …
Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation
TG Schwan, W Burgdorfer, CF Garon - Infection and immunity, 1988 - Am Soc Microbiol
In vitro cultivation of Borrelia burgdorferi, the etiologic agent of Lyme spirochetosis, allows
for the isolation and growth of this bacterium from infected tissues. However, continuous …
for the isolation and growth of this bacterium from infected tissues. However, continuous …
The role of Borrelia burgdorferi outer surface proteins
MR Kenedy, TR Lenhart… - FEMS Immunology & …, 2012 - academic.oup.com
Human pathogenic spirochetes causing Lyme disease belong to the Borrelia burgdorferi
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …
Linear Plasmids of the Bacterium Borrelia burgdorferi Have Covalently Closed Ends
AG Barbour, CF Garon - Science, 1987 - science.org
The genetics of spirochetes, a division of eubacteria, has been little studied. Double-
stranded linear plasmids were found in Borrelia burgdorferi, the agent of Lyme disease. A 49 …
stranded linear plasmids were found in Borrelia burgdorferi, the agent of Lyme disease. A 49 …
Epidemiology and clinical manifestations of Lyme borreliosis in childhood: a prospective multicentre study with special regard to neuroborreliosis
HJ Christen, F Hanefeld, H Eiffert… - Acta paediatrica, 1993 - Wiley Online Library
Lyme borreliosis is a tick‐borne infection caused by the spirochete Borrelia burgdorferi,
whose discovery in 1982 solved an aetiological mystery involving a variety of dcrmatological …
whose discovery in 1982 solved an aetiological mystery involving a variety of dcrmatological …
The burgeoning molecular genetics of the Lyme disease spirochaete
PA Rosa, K Tilly, PE Stewart - Nature Reviews Microbiology, 2005 - nature.com
Lyme disease is the most commonly reported vector-borne disease in North America and
Europe, yet we know little about which components of the causative agent, Borrelia …
Europe, yet we know little about which components of the causative agent, Borrelia …
Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi
RA Kalish, JM Leong, AC Steere - Infection and immunity, 1993 - Am Soc Microbiol
Chronic Lyme arthritis that is unresponsive to antibiotic therapy is associated with an
increased frequency of the HLA-DR4 specificity. To determine whether the immune …
increased frequency of the HLA-DR4 specificity. To determine whether the immune …
Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins
ME Brandt, BS Riley, JD Radolf… - Infection and …, 1990 - Am Soc Microbiol
The pathogenic spirochete Borrelia burgdorferi contains a set of integral membrane proteins
which were selectively extracted into the detergent phase upon solubilization of intact B …
which were selectively extracted into the detergent phase upon solubilization of intact B …