[HTML][HTML] HIV infection and AIDS in sub-Saharan Africa: current status, challenges and opportunities

ABM Kharsany, QA Karim - The open AIDS journal, 2016 - ncbi.nlm.nih.gov
Global trends in HIV infection demonstrate an overall increase in HIV prevalence and
substantial declines in AIDS related deaths largely attributable to the survival benefits of …

Comparative assessment of five trials of universal HIV testing and treatment in sub‐Saharan Africa

D Perriat, L Balzer, R Hayes, S Lockman… - Journal of the …, 2018 - Wiley Online Library
Abstract Design Universal voluntary HIV counselling and testing followed by prompt
initiation of antiretroviral therapy (ART) for all those diagnosed HIV‐infected (universal test …

[HTML][HTML] Antiretroviral therapy for the prevention of HIV-1 transmission

MS Cohen, YQ Chen, M McCauley… - … England Journal of …, 2016 - Mass Medical Soc
Background An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052
trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked …

Effect of universal testing and treatment on HIV incidence—HPTN 071 (PopART)

RJ Hayes, D Donnell, S Floyd, N Mandla… - … England Journal of …, 2019 - Mass Medical Soc
Background A universal testing and treatment strategy is a potential approach to reduce the
incidence of human immunodeficiency virus (HIV) infection, yet previous trial results are …

Can the UNAIDS 90-90-90 target be achieved? A systematic analysis of national HIV treatment cascades

J Levi, A Raymond, A Pozniak, P Vernazza… - BMJ global …, 2016 - gh.bmj.com
Background In 2014, the Joint United Nations Programme on HIV and AIDS (UNAIDS) and
partners set the '90-90-90 targets'; aiming to diagnose 90% of all HIV positive people …

Universal test and treat and the HIV epidemic in rural South Africa: a phase 4, open-label, community cluster randomised trial

CC Iwuji, J Orne-Gliemann, J Larmarange… - The lancet HIV, 2018 - thelancet.com
Background Universal antiretroviral therapy (ART), as per the 2015 WHO recommendations,
might reduce population HIV incidence. We investigated the effect of universal test and treat …

Uptake of home-based HIV testing, linkage to care, and community attitudes about ART in rural KwaZulu-Natal, South Africa: descriptive results from the first phase of …

CC Iwuji, J Orne-Gliemann, J Larmarange… - PLoS …, 2016 - journals.plos.org
Background The 2015 WHO recommendation of antiretroviral therapy (ART) for all
immediately following HIV diagnosis is partially based on the anticipated impact on HIV …

Tuberculosis prevalence after 4 years of population-wide systematic TB symptom screening and universal testing and treatment for HIV in the HPTN 071 (PopART) …

E Klinkenberg, S Floyd, K Shanaube, L Mureithi… - PLoS …, 2023 - journals.plos.org
Background Tuberculosis (TB) prevalence remains persistently high in many settings, with
new or expanded interventions required to achieve substantial reductions. The HIV …

The importance of context in implementation research

N Edwards, PM Barker - JAIDS Journal of Acquired Immune …, 2014 - journals.lww.com
This article describes the pertinence of context in HIV/AIDS implementation research.
Without attending to context and how it interacts with interventions, national protocols for …

A comprehensive genomics solution for HIV surveillance and clinical monitoring in low-income settings

D Bonsall, T Golubchik, M de Cesare… - Journal of clinical …, 2020 - Am Soc Microbiol
Viral genetic sequencing can be used to monitor the spread of HIV drug resistance, identify
appropriate antiretroviral regimes, and characterize transmission dynamics. Despite …