[HTML][HTML] The regulation of lipokines by environmental factors

D Hernández-Saavedra, KI Stanford - Nutrients, 2019 - mdpi.com
Adipose tissue is a highly metabolically-active tissue that senses and secretes hormonal
and lipid mediators that facilitate adaptations to metabolic tissues. In recent years, the role of …

The functions of Ca2+/calmodulin-dependent protein kinase II (CaMKII) in diabetes progression

K Benchoula, A Mediani, WE Hwa - Journal of Cell Communication and …, 2023 - Springer
The increase in blood glucose causes a myriad of pathways and molecular components to
malfunction, leading to diabetes. Diabetes affects each organ differently by activating distinct …

[HTML][HTML] Myristic acid supplementation aggravates high fat diet-induced adipose inflammation and systemic insulin resistance in mice

V Saraswathi, N Kumar, W Ai, T Gopal, S Bhatt… - Biomolecules, 2022 - mdpi.com
Saturated fatty acids (SFAs) are considered to be detrimental to human health. One of the
SFAs, myristic acid (MA), is known to exert a hypercholesterolemic effect in mice as well as …

Exercise increases hyper-acetylation of histones on the Cis-element of NRF-1 binding to the Mef2a promoter: Implications on type 2 diabetes

JS Joseph, AO Ayeleso, E Mukwevho - Biochemical and biophysical …, 2017 - Elsevier
Exercise brings changes on the chromatin ensuing the upregulation of many genes that
confer protection from type 2 diabetes. In type-2 diabetes, critical genes are down-regulated …

[HTML][HTML] Long-term impact of neonatal intake of oleanolic acid on the expression of AMP-activated protein kinase, adiponectin and inflammatory cytokines in rats fed …

MG Matumba, AO Ayeleso, T Nyakudya, K Erlwanger… - Nutrients, 2019 - mdpi.com
AMP-activated protein kinase (AMPK) is known to regulate both glucose and lipid
metabolism, which play vital roles in the development of metabolic syndrome. One way of …

Role of CaMKII in the regulation of fatty acids and lipid metabolism

JS Joseph, K Anand, ST Malindisa… - Diabetes & Metabolic …, 2021 - Elsevier
Background & aims Previous studies have reported the beneficial roles of the activation of
calmodulin-dependent protein kinase (CaMK) II to many cellular functions associated with …

SS31 confers cerebral protection by reversing mitochondrial dysfunction in early brain injury following subarachnoid hemorrhage, via the Nrf2-and PGC-1α-dependent …

J Zhou, R Shen, EC Makale, W Zhong, Z Chen… - Neurochemical …, 2023 - Springer
In early brain injury (EBI), oxidative stress occurs following subarachnoid hemorrhage
(SAH), and mitochondria are intricately linked to this process. SS31, a mitochondria …

[HTML][HTML] CaMKII activity and metabolic imbalance-related neurological diseases: Focus on vascular dysfunction, synaptic plasticity, amyloid beta accumulation, and …

J Yong, J Song - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Metabolic syndrome (MetS) is characterized by insulin resistance, hyperglycemia, excessive
fat accumulation and dyslipidemia, and is known to be accompanied by neuropathological …

[PDF][PDF] Role of exercise-induced calmodulin protein kinase (CaMK) II activation in the regulation of omega-6 fatty acids and lipid metabolism genes in rat skeletal …

JS Joseph, AO Ayeleso, E Mukwevho - Physiol. Res, 2017 - academia.edu
Activation of calmodulin dependent protein kinase (CaMK) II by exercise is beneficial in
controlling membrane lipids associated with type 2 diabetes and obesity. Regulation of lipid …

[HTML][HTML] A Study on Neonatal Intake of Oleanolic Acid and Metformin in Rats (Rattus norvegicus) with Metabolic Dysfunction: Implications on Lipid Metabolism and …

M Molepo, A Ayeleso, T Nyakudya, K Erlwanger… - Molecules, 2018 - mdpi.com
Metabolic syndrome, a cluster of different disorders which include diabetes, obesity and
cardiovascular diseases, is a global epidemic that is growing at an alarming rate. The …