In patients with multiple sclerosis (MS), grey matter damage is widespread and might
underlie many of the clinical symptoms, especially cognitive impairment. This relation …

Neuropsychiatric abnormalities may be broadly divided in two categories: disorders of
mood, affect, and behavior and abnormalities affecting cognition. Among these conditions …

Background Random forest based variable importance measures have become popular
tools for assessing the contributions of the predictor variables in a fitted random forest. In this …

MRI studies have provided valuable insights into the structure and function of neural
networks, particularly in health and in classical neurodegenerative conditions such as …

Objectives: To assess the value of conventional and magnetization transfer (MT) MRI
measures of white matter (WM) and gray matter (GM) damage, and their 12-month change …

This short review examines the most recent functional studies of the topographic
organization of the human corpus callosum, the main interhemispheric commissure. After a …

Abstract Although Alois Alzheimer described myelin disruption in Alzheimer's disease (AD)
as early as in 1911, his observation has escaped the attention of researchers since that time …

Objective: To investigate whether extent and severity of white matter (WM) damage, as
measured with diffusion tensor imaging (DTI), can distinguish cognitively preserved (CP) …

MRI has become the most important paraclinical tool for diagnosing and monitoring patients
with multiple sclerosis (MS). However, conventional MRI sequences are largely nonspecific …

Alzheimer's disease (AD) involves a gradual breakdown of brain connectivity, and network
analyses offer a promising new approach to track and understand disease progression …